… Interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-2 production, as well
as expression of the degranulation marker CD107a on tumor-specific CD8+ T cells, were …

… In summary, we have shown that immunodominant TAA-specific CD8+ T-cell responses
in HCC patients are spread across multiple antigens and associated with patient survival. …

… HCC-specific CD8 T cell responses in patients with HCC. Taken together, our results show
the presence of AFPspecific CD8 T cell responses in patients with HCC. … in the HCC lesions. …

… molecules expressed on these cells could have a substantial … discuss the specific CD8 +
T cell response during HCC and … by tumoural cells and hepatotropic viruses to induce T cell …

… Treg inhibit granule production of infiltrating CD8 + T cells obtained from the same tumor
specimen, resulting in an inability of tumor-specific CD8 + T cells to kill autologous tumor cells. …

… -specific CD8 + T cells in the current study provides further evidence that this occurs in HCC.
… CD8 + T cells and activation by its ligand PDL-1 in the tumor environment contributes to T-…

… of AFP-specific CD8 T cells in the liver of HCC patients is no … tumor specific CD8 T cells
are generally enriched in the liver[24]. It is possible that liver infiltrating AFP-specific CD8 T cells …

… + CD8 + T cells is not mainly due to HBV-specific CD8 + T cells. The percentages of PD1-expressing
total and TAA-specific CD8 + T cells … the 2 subgroups of HCC patients (Figure 6C). …

… TAA-specific CD8 + T cells express relatively high … -specific CD8 + T cells in patients
with HCC.34, 35 The selectively increased expression of these inhibitory receptors on TAA-specific …

… -specific CD8 cells in patients with HCC, the high expression rate of MAGE genes in
hepatocellular carcinoma, the infiltration of the tumor tissue by a dominant CD8+ T cell population …