CIRI: an efficient and unbiased algorithm for de novo circular RNA identification
… The expression of a specific circRNA type is represented by the count of junction reads
normalized by total sequencing amount in each cell type. The boxplot is generated by R using ln(…
normalized by total sequencing amount in each cell type. The boxplot is generated by R using ln(…
Intriguing circles: conflicts and controversies in circular RNA research
HM Li, XL Ma, HG Li - Wiley Interdisciplinary Reviews: RNA, 2019 - Wiley Online Library
… ability is not a general circRNA phenomenon and might be limited to specific circRNAs.
To be a better miRNA sponge, the result of the formula circRNA molecules × miRNA binding …
To be a better miRNA sponge, the result of the formula circRNA molecules × miRNA binding …
Using circular RNA as a novel type of biomarker in the screening of gastric cancer
P Li, S Chen, H Chen, X Mo, T Li, Y Shao, B Xiao… - Clinica chimica acta, 2015 - Elsevier
… These results suggested that circRNAs are highly stable in mammalian cells and that one
specific circRNA, hsa_circ_002059, may be a potential novel and stable biomarker for the …
specific circRNA, hsa_circ_002059, may be a potential novel and stable biomarker for the …
The biogenesis and emerging roles of circular RNAs
LL Chen - Nature reviews Molecular cell biology, 2016 - nature.com
… -seq and specific computational pipelines that aim to identify reads spanning the back-…
to be highly expressed in a cell type-specific or tissue-specific manner 16,17 . Furthermore, …
to be highly expressed in a cell type-specific or tissue-specific manner 16,17 . Furthermore, …
A map of human circular RNAs in clinically relevant tissues
… By identifying and validating selected circRNAs in these human tissues relevant to clinical
research, we provide multiple examples of abundant and highly tissue-specific circRNA …
research, we provide multiple examples of abundant and highly tissue-specific circRNA …
Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs
M Ron, I Ulitsky - Nature communications, 2022 - nature.com
… of specific RNA … of circular RNAs; SAFB binding is associated with nuclear enrichment
of predominantly unspliced linear RNAs; and IGF2BP1 promotes export of linear spliced RNA …
of predominantly unspliced linear RNAs; and IGF2BP1 promotes export of linear spliced RNA …
Structured elements drive extensive circular RNA translation
The human genome encodes tens of thousands circular RNAs (circRNAs) with mostly
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
unknown functions. Circular RNAs require internal ribosome entry sites (IRES) if they are to …
Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective
… We summarize different molecular mechanisms of action and highlight circRNAs with
specific roles in cardiovascular disease. Finally, we describe a number of tools for …
specific roles in cardiovascular disease. Finally, we describe a number of tools for …
Circular RNA: an emerging non-coding RNA as a regulator and biomarker in cancer
B Chen, S Huang - Cancer letters, 2018 - Elsevier
… TSCD (http://gb.whu.edu.cn/TSCD/ ) provides a global view of tissue-specific circRNA in
the tissues of humans and mice and is able to contribute to identifying new markers for …
the tissues of humans and mice and is able to contribute to identifying new markers for …
[HTML][HTML] Cell type-specific circular RNA expression in human glial cells
… The circular transcriptome of human glial cells is an area of … Circular RNAs (circRNAs)
have the potential to facilitate the … RNA-seq data utilized in this paper are suitable for circRNA …
have the potential to facilitate the … RNA-seq data utilized in this paper are suitable for circRNA …