Mass spectrometry imaging of pharmacological compounds in tissue sections
RJA Goodwin, AR Pitt - Bioanalysis, 2010 - Future Science
… periods to the field of pharmacology and biomarker imaging research. By collecting spectra
… Compound and metabolite distribution measured by MALDI mass spectrometric imaging in …
… Compound and metabolite distribution measured by MALDI mass spectrometric imaging in …
Mass spectrometry imaging in drug development
… technologies are superior to established methods for studying compound localization and …
through the BBB in order to exert their pharmacological effects, and treatment failures in these …
through the BBB in order to exert their pharmacological effects, and treatment failures in these …
Drug compound characterization by mass spectrometry imaging in cancer tissue
HJ Kwon, Y Kim, Y Sugihara, B Baldetorp… - Archives of pharmacal …, 2015 - Springer
… pharmacological activities of the drug. The potentially beneficial or toxic effects of such drug
therapy are determined by the unique chemical and pharmacological … spectrometry imaging (…
therapy are determined by the unique chemical and pharmacological … spectrometry imaging (…
Spatial pharmacology using mass spectrometry imaging
P Rajbhandari, TV Neelakantan, N Hosny… - … in Pharmacological …, 2024 - cell.com
… This is enabled by mass spectrometry imaging (MSI) that … potential of comprehensive spatial
pharmacology through integration of … improving reproducibility and compound annotation to …
pharmacology through integration of … improving reproducibility and compound annotation to …
Mass spectrometry imaging: new eyes on natural products for drug research and development
J Hou, Z Zhang, W Wu, Q He, T Zhang, Y Liu… - Acta Pharmacologica …, 2022 - nature.com
… imaging technologies can detect thousands of compounds simultaneously on a label-free
basis. Over the last two decades, mass spectrometry imaging … distribution and pharmacological …
basis. Over the last two decades, mass spectrometry imaging … distribution and pharmacological …
Mass spectrometric imaging of small molecules
A Svatoš - Trends in biotechnology, 2010 - cell.com
… The compounds are introduced to spectrometers directly, or … ), to allow mixtures of compounds
to be separated before mass … A more advanced way to confirm compound identity and to …
to be separated before mass … A more advanced way to confirm compound identity and to …
Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance
M Jove, J Spencer, M Clench, PM Loadman… - Critical reviews in …, 2019 - Elsevier
… the tumour, “precision pharmacology” techniques are needed. Mass spectrometry imaging
(MSI) is a relatively new and complex technique that allows imaging of drug distribution within …
(MSI) is a relatively new and complex technique that allows imaging of drug distribution within …
Future technology insight: mass spectrometry imaging as a tool in drug research and development
… , pharmacodynamics and transport properties of compounds in tissues is crucial … spectrometry
imaging (MSI) can discriminate drug and its metabolites and endogenous compounds…
imaging (MSI) can discriminate drug and its metabolites and endogenous compounds…
Innovation in drug toxicology: Application of mass spectrometry imaging technology
H Jiang, S Gao, G Hu, J He, H Jin - Toxicology, 2021 - Elsevier
… mass spectrometry imaging (MSI) technology can overcome the above limitations and provide
relative abundance information of compounds … , and the pharmacological or toxicological …
relative abundance information of compounds … , and the pharmacological or toxicological …
[HTML][HTML] The application of mass spectrometry imaging in traditional Chinese medicine: a review
L Huang, L Nie, Z Dai, J Dong, X Jia, X Yang, L Yao… - Chinese Medicine, 2022 - Springer
… traditional Chinese medicine, discover new compounds from traditional herbs, and differentiate
… Moreover, mass spectrometry imaging also plays a role in revealing the pharmacological …
… Moreover, mass spectrometry imaging also plays a role in revealing the pharmacological …
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