Sperm chromatin structure and male fertility: biological and clinical aspects

J Erenpreiss, M Spano, J Erenpreisa… - Asian journal of …, 2006 - Wiley Online Library
… Aim: Sperm chromatin/DNA integrity is essential for the … sperm chromatin structure is
important for sperm fertilizing ability. The routine examination of semen, which includes sperm

Function of sperm chromatin structural elements in fertilization and development

WS Ward - MHR: Basic science of reproductive medicine, 2009 - academic.oup.com
sperm chromatin structure and function have altered our perception of this highly condensed,
inert chromatin… see, this is not true for the other two levels of sperm chromatin structure. The …

The sperm chromatin structure assay: a review of clinical applications

CC Love - Animal reproduction science, 2005 - Elsevier
… A variety of factors have been reported to negatively affect sperm motility of extended …
factors on sperm chromatin has not been adequately addressed. Apparently, some sperm may …

The structural organization of sperm chromatin

SM Wykes, SA Krawetz - Journal of Biological Chemistry, 2003 - ASBMB
… Interestingly, this configuration persists in mature spermatozoa subsequent to … sperm may
be preferentially histone-enriched. To address this tenet, we examined the chromatin structure

Sperm chromatin structure assay (SCSA®)

DP Evenson - Spermatogenesis: methods and protocols, 2013 - Springer
The SCSA ® is the pioneering assay for the detection of damaged sperm DNA and altered
proteins in sperm nuclei via flow cytometry of acridine orange (AO) stained sperm. The SCSA …

Biology of sperm chromatin structure and relationship to male fertility and embryonic survival

MJ D'occhio, KJ Hengstberger, SD Johnston - Animal reproduction science, 2007 - Elsevier
chromatin status in sperm but arguably the most informative is the sperm chromatin structure
… orange to measure the susceptibility of sperm chromatin to acid-induced denaturation. A …

[HTML][HTML] Correlation between sperm motility and sperm chromatin structure assay parameters

A Giwercman, J Richthoff, H Hjøllund, JP Bonde… - Fertility and sterility, 2003 - Elsevier
… anomalies of the structural organization of sperm DNA and have … FCM methods, the sperm
chromatin structure assay (SCSA) … chromatin structure as an increased susceptibility of sperm

[PDF][PDF] Sperm chromatin

G Fuentes-Mascorro, H Serrano, A Rosado - Archives of andrology, 2000 - Taylor & Francis
… most remarkable changes in chromatin structure observed in … structural characteristics of
the DNA in the sperm chromatin … that sperm DNA has some important structural properties that …

Sperm chromatin structure assay and classical semen parameters: systematic review

JA Castilla, S Zamora, MC Gonzalvo… - Reproductive …, 2010 - Elsevier
male fertility potential. Among such tests are those based on an analysis of DNA stainability
to estimate DNA damage or fragmentation. The introduction of the sperm chromatin structure

Sperm chromatin structure assay: DNA denaturability

D Evenson, L Jost - Methods in cell biology, 1994 - Elsevier
… -complexed DNA in sperm with abnormal chromatin structure do not cause denaturation of
sperm chromatin structure as described here has been termed the sperm chromatin structure