The effects of exogenously administered testosterone on spermatogenesis in intact and hypophysectomized rats

YUNT SUN, DANC IRBY, DM ROBERTSON… - …, 1989 - academic.oup.com
doses of testosterone (>10-cm implants) may reflect a decline in the number of spermatogenic
cell … response, with very low intratesticular and supraphysiological serum testosterone lev- …

Failure of Spermatogenesis to Recover Despite the Presence of A Spermatogonia in the Irradiated LBNF1 Rat

M Kangasniemi, I Huhtaniemi… - Biology of …, 1996 - academic.oup.com
… At 4-6 wk after irradiation at all doses tested, there was a gap in which spermatogenic cells
were … In monkeys, supraphysiological doses of FSH augmented the numbers of both A and B …

[HTML][HTML] Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors during Endometrial Receptivity Development in …

AN Muhammad Yusuf, MF Amri, A Ugusman… - International Journal of …, 2024 - mdpi.com
This study aims to investigate the effect of a supraphysiological dose of … In this study, treatment
with a supraphysiological dose of … This study shows that a supraphysiological dose of …

Testosterone promotes the conversion of round spermatids between stages VII and VIII of the rat spermatogenic cycle

L O'Donnell, RI McLachlan, NG Wreford… - …, 1994 - academic.oup.com
… rats at a dose producing slightly supraphysiological serum T levels… The structural and cellular
changes associated with sper… In previous studies we have analyzed the spermatogenic cell

Gonadotropin-releasing hormone analogues for prostate cancer: untoward side effects of high-dose regimens acquire a therapeutical dimension

GH Jacobi, UK Wenderoth - European Urology, 1982 - karger.com
… Gn-RH agonists, spermatogenesis, arrested at the primary … spermatogenesis and androgen
syn thesis is supressed. … in a daily dose of 0.05 pg/kg (a), and in supraphysiological doses of …

17Beta-estradiol triggers postspawning in spermatogenically active gilthead seabream (Sparus aurata L.) males

E Chaves-Pozo, S Liarte, L Vargas-Chacoff… - Biology of …, 2007 - academic.oup.com
… Bearing this in mind, we exposed gilthead seabream males to supraphysiological doses of E
… increase in spermatogonia stem cell proliferation triggered by a supraphysiological dose of …

Leptin within the subphysiological to physiological range dose dependently improves male reproductive function in an obesity mouse model

A Hoffmann, GM Manjowk, IV Wagner, N Klöting… - …, 2016 - academic.oup.com
doses improve spermatogenesis markers. Leptin significantly increased the number of tubules
in the first half of the spermatogenic … the effects of supraphysiological leptin concentrations…

Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice

J Singh, C O'Neill, DJ Handelsman - Endocrinology, 1995 - academic.oup.com
… The androgen dosage used in this study aimed to cover a wide range of circulating androgen
levels and included DHT, a … The concomitance of supraphysiological blood T concentra- …

[HTML][HTML] Effect of rejuvenation hormones on spermatogenesis

JL Moss, LE Crosnoe, ED Kim - Fertility and sterility, 2013 - Elsevier
… These doses are supraphysiologic in that they are 50 to 100 times greater than the 40–50
mg weekly production of testosterone by the normal male testes (24). Biological potency of …

Cisplatin-induced alterations in the functional spermatogonial stem cell pool and niche in C57/BL/6J mice following a clinically relevant multi-cycle exposure

JG Harman, JH Richburg - Toxicology Letters, 2014 - Elsevier
… regenerative capacity of spermatogonia germ cell sub-types … examined in response to
cisplatin dosing by Foxo1 staining, … , but reached a supraphysiological level by the conclusion of …