Vaccination with SPf66, a chemically synthesised vaccine, against Plasmodium falciparum malaria in Colombia

MV Valero, LR Amador, C Galindo, J Figueroa… - The Lancet, 1993 - Elsevier
… between the two groups can only be attributed to the potential of SPf66 to modify the risk of
malaria. The results of our trial confirm that the chemically synthesised SPf66 vaccine is safe, …

Vaccines for preventing malaria (SPf66)

PM Graves, H Gelband… - Cochrane Database …, 1996 - cochranelibrary.com
vaccines (Graves 2006b). This review considers trials of SPf66 vaccine, while other types of
malaria vaccine are … vaccines will also be prepared when they have reached the trial stage. …

Efficacy trial of malaria vaccine SPf66 in Gambian infants

U D'alessandro, A Leach, BO Olaleye, GW Fegan… - The lancet, 1995 - thelancet.com
malariaSPf66 against clinical P falciparum malaria in Gambian infants. 630 children, aged
6-11 months at time of the first dose, received three doses of SPf66 or injected polio vaccine (…

SPf66 malaria vaccine is safe and immunogenic in malaria naive adults in Thailand

S Migasena, DG Heppner, DE Kyle… - Acta tropica, 1997 - Elsevier
… This initial study of SPf66 malaria vaccine in Asia constitutes an essential link … malaria
endemic area of Thailand. This study further establishes comparability of US-manufactured SPf66

Evaluation of SPf66 malaria vaccine efficacy in Brazil

M Urdaneta, A Prata, CJ Struchiner, CE Tosta, P Tauil… - 1998 - arca.fiocruz.br
… This paper reports the efficacy results of the randomized, placebo-controlled, field trial of
SPf66 malaria vaccine in Costa Marques, Rondonia, Brazil. This region is characterized by the …

Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant …

O Kashala, R Amador, MV Valero, A Moreno… - Vaccine, 2002 - Elsevier
SPf66 is a synthetic malaria peptide vaccine, which has been widely … SPf66/QS-21 vaccines
were evaluated for safety, tolerability and immunogenicity in healthy adults. The vaccines

The first field trials of the chemically synthesized malaria vaccine SPf66: safety, immunogenicity and protectivity

R Amador, A Moreno, V Valero, L Murillo, AL Mora… - Vaccine, 1992 - Elsevier
… and protectivity of the synthetic malaria vaccine SPf66 directed against the asexual blood …
directed against the SPf66 molecule. Two of the 185 (1.08%) SPf66-vaccinated and nine of …

Safety and immunogenicity of the synthetic malaria vaccine SPf66 in a large field trial

R Amador, A Moreno, LA Murillo… - Journal of Infectious …, 1992 - academic.oup.com
… A descriptive study was done to evaluate the safety and immunogenicity of the SPf66 malaria
vaccine: 86 localities, distributed in 10 geographic areas from the Tumaco and Francisco …

Malaria vaccines

R Amador, ME Patarroyo - Journal of clinical immunology, 1996 - Springer
malaria vaccine (19-21). In a phase II trial of the five individuals immunized with the Spf66
vaccine … To evaluate the safety, immunogenicity, and efficacy of the SPf 66 malaria vaccine

Evaluation of the SPf66 vaccine for malaria control when delivered through the EPI scheme in Tanzania

CJ Acosta, CM Galindo, D Schellenberg… - Tropical Medicine & …, 1999 - Wiley Online Library
… As part of the programme to evaluate SPf66 as a potential tool for malaria control in Africa,
initiated in 1992, we conducted a trial designed to evaluate the efficacy of SPf66 when …