… the elevation of sphingoid bases by FB1 and AP1 and the reduction in cell number. For
example, 10 μM FB1 and 50 μM AP1 elevated sphingoid bases (sphingosine sphinganine) by 70 …

… turnover to bioactive metabolites including sphingoid bases (sphingosine and sphinganine)
… effects of sphingoid bases and ceramides on the growth, death, and cell cycle of HT-29 and …

… as ceramide and/or sphingoid bases, and induce apoptosis by stimulating JNK activity.
Our findings might suggest that the sphingoid base sphinganine might mediate the apoptotic …

… of the sphingoid base with O-phthaldehyde following deacylation of ceramide as characterized
previously [35]. The aqueous phase containing glycolipids was loaded in a Sep-Pak C18 …

… ) or high-performance liquid chromatography (HPLC) after derivatization of the sphingoid
base with o-phthalaldehyde following deacylation of ceramide as characterized previously [27]. …

… We show here the sphingoid base composition of … The composition of sphingoid bases
prepared from sea cucumber … cells treated with sea cucumber sphingoid bases was reduced in a …

… of sphingoid bases from plant and fungus sphingolipids and the mechanisms involved.
Sphingoid bases … by sphingoid bases was noted to occur. The Caspase-3 inhibitor suppressed …

… (bottom panel) in Caco-2 cells and HT 29 cells cultured in monolayer and on the insert filter.
… foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. …

… sphingoid bases and C 2 -ceramide at 35 μM for 24 h induced apoptosis. In the current study,
sphingoid bases … was slightly smaller than that of the sphingoid bases applied for 24 h. In …

… Sphingosine, sphinganine, and ceramide inhibit growth and cause death of HT29 human
colon cancer cells. Subconfluent cells were cultured with sphingosine (A), sphinganine (B), C2 …