… to a porous multiple channel bridge, with channels of varying diameter, implanted in a rat
spinal cord hemisection model. Multiple channel bridges with controlled pore size and …

… Spinal cord injury (SCI) results in loss of sensory and motor function … bridges containing
seven channels with a diameter of 250 μm were implanted in a rat spinal cord hemisection injury. …

… In this report, we investigate delivery of lentiviral vectors from multiple channel bridges as
a … delivery from multiple channel PLG bridges in a rat spinal cord hemisection injury model. …

… spinal cord regeneration, bridges with multiple channels orient the extension of axons across
an injury [2], [3], [4], [5], [6], while gene delivery from the bridges … The spinal cord, however, …

… multiple channel bridges were developed with the goal of investigating a permissive
environment for spinal cord … The bridges were made of PLG, which is biodegradable and has …

… (lipoplexes) from a multiple channel bridge in order to promote transgene expression in the
… The spinal cord bridges used in this report contain multiple linear guidance channels and …

… investigated multichannel poly(lactide-co-glycolide) bridges, … of E14 spinal progenitors on
multichannel PLG bridges with the … and through the injury. We successfully delivered a modest …

… apposition of PLG multichannel bridges with the spared spinal cord parenchyma following a
… Taken together, these data suggest that PLG bridges in a cervical mouse spinal cord lesion …

… as a second predictor variable (p=0.030) for the subgroup showing a width of ventral tissue
bridges ≤2.1 mm and separated it into two more nodes with ≤1.62 mm (n=24, node 3) and >…

… After spinal cord InJury (SCI), many damaging tissue processes are initiated that lead to …
that they enabled axons to leave the SC bridge to grow into the spinal cord (24). They also have …