Polysialic acid glycomimetic promotes functional recovery and plasticity after spinal cord injury in mice
A Mehanna, I Jakovcevski, A Acar, M Xiao, G Loers… - Molecular Therapy, 2010 - cell.com
… numbers in the lumbar spinal cord, ie caudal to … spinal cord. (a) Individual choline
acetyltransferase (ChAT + ) motoneurons in the lumbar spinal cord of mice treated with polysialic …
acetyltransferase (ChAT + ) motoneurons in the lumbar spinal cord of mice treated with polysialic …
Polysialic-acid-based micelles promote neural regeneration in spinal cord injury therapy
XJ Wang, CH Peng, S Zhang, XL Xu, GF Shu, J Qi… - Nano Letters, 2019 - ACS Publications
… permeability and blood-spinal cord barrier damage caused … spinal cord was higher than
that of the liver at 12 and 24 h after injection. To specifically assess the distribution in spinal cord …
that of the liver at 12 and 24 h after injection. To specifically assess the distribution in spinal cord …
Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord
Y Zhang, X Zhang, D Wu, J Verhaagen… - Molecular Therapy, 2007 - cell.com
… the spinal cord. In this study we examined whether, by inducing expression of polysialic acid
(PSA) (a large carbohydrate attached to molecules on the cell surface), in the spinal cord by …
(PSA) (a large carbohydrate attached to molecules on the cell surface), in the spinal cord by …
Extensive cell migration, axon regeneration, and improved function with polysialic acid‐modified Schwann cells after spinal cord injury
… Schwann cell (SC) implantation after spinal cord injury (SCI) promotes axonal regeneration,
… Altering SC cell surface properties by overexpressing polysialic acid (PSA) has been shown …
… Altering SC cell surface properties by overexpressing polysialic acid (PSA) has been shown …
Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice
HC Pan, YQ Shen, G Loers, I Jakovcevski… - Neuroscience, 2014 - Elsevier
… In the present study, a mouse spinal cord compression device was used to … spinal cord
injury compared to the control group receiving vehicle only. Immunohistology of the spinal cord …
injury compared to the control group receiving vehicle only. Immunohistology of the spinal cord …
A polysialic acid mimetic peptide promotes functional recovery in a mouse model of spinal cord injury
P Marino, JC Norreel, M Schachner, G Rougon… - Experimental …, 2009 - Elsevier
… , functional recovery after spinal cord injury is impaired by a non-… alpha 2,8-linked sialic acid
(PolySialic Acid, PSA), represents a … Selection of poly-alpha 2,8-sialic acid mimotopes from a …
(PolySialic Acid, PSA), represents a … Selection of poly-alpha 2,8-sialic acid mimotopes from a …
Induced expression of polysialic acid in the spinal cord promotes regeneration of sensory axons
Y Zhang, M Ghadiri-Sani, X Zhang… - Molecular and Cellular …, 2007 - Elsevier
… After spinal cord injury axonal regeneration is prevented by glial … polysialic acid (PSA) in
the lesion site would render the glial scar permissive to axonal regeneration after dorsal column …
the lesion site would render the glial scar permissive to axonal regeneration after dorsal column …
Polycaprolactone/polysialic acid hybrid, multifunctional nanofiber scaffolds for treatment of spinal cord injury
S Zhang, XJ Wang, WS Li, XL Xu, JB Hu, XQ Kang, J Qi… - Acta biomaterialia, 2018 - Elsevier
… the spinal cord lesion sites for inhibiting inflammatory response [31]. Currently, polysialic acid
(… is consisting of α-2, 8-linked sialic acid units, shows great potential in modulating cell–cell …
(… is consisting of α-2, 8-linked sialic acid units, shows great potential in modulating cell–cell …
Use of polysialic acid in repair of the central nervous system
A El Maarouf, AK Petridis… - Proceedings of the …, 2006 - National Acad Sciences
… Dorsal view of spinal cord showing the location of the right unilateral lesion of the dorsal …
(E) A cresyl violet-stained sagittal section of the spinal cord showing the lesioned area. The …
(E) A cresyl violet-stained sagittal section of the spinal cord showing the lesioned area. The …
Polysialic acid in the rat brainstem and thoracolumbar spinal cord: Distribution, cellular location, and comparison with mouse
… , di-, or oligo-sialic acid, three regions with high expression of … that degrades linear polymers
of sialic acid only with α2,8-… the main sialic acid present in the brainstem and spinal cord. …
of sialic acid only with α2,8-… the main sialic acid present in the brainstem and spinal cord. …
相关搜索
- thoracolumbar spinal cord polysialic acid
- spinal cord injury
- regeneration of sensory axons polysialic acid
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- cell interactions polysialic acid
- low molecular weight polysialic acid
- role of polysialic acid
- contused spinal cord
- spinal cord repair and regeneration
- length and quantity polysialic acids
- neuronal and glial functions polysialic acid
- transplanted schwann cells polysialic acid
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- thoracolumbar spinal cord comparison with mouse
- subject category polysialic acids
- lentiviral mediated expression polysialic acid