[HTML][HTML] Systematic review of somatic mutations in splenic marginal zone lymphoma
C Jaramillo Oquendo, H Parker, D Oscier, S Ennis… - Scientific reports, 2019 - nature.com
… somatic variants in splenic marginal zone lymphoma (SMZL) and to provide a well-annotated,
manually curated database of high-confidence somatic mutations … and TP53 mutations and …
manually curated database of high-confidence somatic mutations … and TP53 mutations and …
Analysis of the IgVH somatic mutations in splenic marginal zone lymphoma defines a group of unmutated cases with frequent 7q deletion and adverse clinical …
P Algara, MS Mateo, M Sanchez-Beato… - Blood, The Journal …, 2002 - ashpublications.org
… of somatic mutations in the … of splenic marginal zone lymphoma (SMZL). The cases were
studied by seminested polymerase chain reaction by using primers from the FR1 and J H region…
studied by seminested polymerase chain reaction by using primers from the FR1 and J H region…
V H gene analysis of splenic marginal zone lymphomas reveals diversity in mutational status and initiation of somatic mutation in vivo
D Zhu, J Orchard, DG Oscier, DH Wright… - Blood, The Journal …, 2002 - ashpublications.org
… somatic mutation, with clear intraclonal heterogeneity. To our knowledge, this is the first case
of a B-cell tumor showing initiation of somatic mutation in … influence tumor cell behavior and …
of a B-cell tumor showing initiation of somatic mutation in … influence tumor cell behavior and …
[HTML][HTML] BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas
Q Yan, Y Huang, AJ Watkins, S Kocialkowski… - …, 2012 - ncbi.nlm.nih.gov
… 1 of 12 splenic marginal zone lymphomas. To … splenic marginal zone lymphoma, we screened
several NF-κB regulators for genetic changes by PCR and sequencing. Somatic mutations …
several NF-κB regulators for genetic changes by PCR and sequencing. Somatic mutations …
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype
A Clipson, M Wang, L De Leval, M Ashton-Key… - Leukemia, 2015 - nature.com
… the genetics of splenic marginal zone lymphoma (SMZL), we … identified novel recurrent
inactivating mutations in Kruppel-like … somatic mutation, suggesting origination of these lymphoma …
inactivating mutations in Kruppel-like … somatic mutation, suggesting origination of these lymphoma …
Genetics and prognostication in splenic marginal zone lymphoma: revelations from deep sequencing
… For this analysis, we again only focused on variation in genes known to be targeted by
somatic mutations in SMZL. We identified 12 variants, and after accounting for tumor purity, these …
somatic mutations in SMZL. We identified 12 variants, and after accounting for tumor purity, these …
Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma
… In summary, we used WGS to reveal high-frequency recurrent somatic mutations involving
… mutations appear to be specific for marginal zone lymphomas as compared with other B cell …
… mutations appear to be specific for marginal zone lymphomas as compared with other B cell …
Splenic marginal zone lymphoma
MA Piris, A Onaindia, M Mollejo - Best Practice & Research Clinical …, 2017 - Elsevier
… into marginal zone B cells and to acquire somatic mutations … somatic mutations may allow
identifying these MCL with a more indolent behavior [73]. Primary splenic follicular lymphoma …
identifying these MCL with a more indolent behavior [73]. Primary splenic follicular lymphoma …
MYD88 (L265P) somatic mutation in marginal zone B-cell lymphoma
A Martinez-Lopez, S Curiel-Olmo… - The American journal …, 2015 - journals.lww.com
… chain reaction for sensitive detection of this mutation in paraffin-embedded tissue. We …
with splenic marginal zone lymphoma (SMZL), 8 patients with nodal marginal zone lymphoma (…
with splenic marginal zone lymphoma (SMZL), 8 patients with nodal marginal zone lymphoma (…
Splenic marginal zone lymphoma with villous lymphocytes shows on-going immunoglobulin gene mutations
A Tierens, J Delabie, A Malecka, J Wang… - The American journal of …, 2003 - Elsevier
… Splenic marginal zone lymphoma (also splenic lymphoma with villous lymphocytes) is a B-cell
non-Hodgkin's lymphoma … respect to the presence of somatic mutations, which has been …
non-Hodgkin's lymphoma … respect to the presence of somatic mutations, which has been …
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