… about sequences and structure of mRNA transcripts is very limited. The genome is … , splice
isoforms, APA sites and fusion transcripts are largely unclear. Here we used SMRT to analyze …

… of the whole gene also showed further changes in splicing, transcript termination and/or
transcript initiation, suggesting that transcript isoform variation constitutes a large part of the …

… Analysis of transcript expression over the time series revealed complete switches in the
dominant transcription start site (TSS) or splice-isoform in 330 genes, along with more subtle …

… analyze alfalfa transcriptome. To evaluate leaf development and ensure wide coverage of
transcript isoforms, … stages were mixed for transcriptome analysis by SMRT. The transcriptome …

… Here we report an in-depth analysis of 15 diverse human … transcript events’ 1,2 , each
capable of producing multiple mRNA isoforms from human genes through alternative splicing, …

… filter; we excluded some isoforms that went undetected in the proteomics analyses from the
… To capture differences between isoforms at the transcript level, we created a score from RNA…

… spliced isoforms, and we discuss their applications in developmental and cancer biology. We
outline future directions for isoform … High-throughput analyses of transcript-level data have …

… AS of precursor messenger RNAs (pre-mRNAs) can generate different transcript isoforms
by selection of alternative splice sites (1–3). A major consequence of AS is that mRNA variants …

… We analyzed transcript isoform diversity across … analysis highlights two important aspects
of RNA splicing. First, alternative splicing is not the main process by which transcript isoform …

… to unravel differential transcript usage, such as annotation-based exon-level counting,
differential analysis of the percentage spliced in, or quantitative analysis of assembled transcripts. …