[HTML][HTML] TRPV1 splice variants: structure and function

MA Schumacher, H Eilers - Frontiers in bioscience (Landmark …, 2010 - ncbi.nlm.nih.gov
… With the isolation of the capsaicin receptor, now known as TRPV1 (transient receptor potential
vanilloid subtype -1 channel), our understanding of peripheral sensory transduction has …

[HTML][HTML] … cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal domain suggests functional divergence among capsaicin receptor …

MA Schumacher, I Moff, SP Sudanagunta… - Journal of Biological …, 2000 - ASBMB
… that is activated by both capsaicin, the pain … receptor-like protein that is responsive to high
temperatures (52–53 C). Here, we report the isolation of a vanilloid receptor 5′-splice variant (…

TRPV1b, a functional human vanilloid receptor splice variant

G Lu, D Henderson, L Liu, PH Reinhart… - Molecular pharmacology, 2005 - ASPET
… by diverse stimuli, including capsaicin, lipids, … RNA splice variant, TRPV1b, which forms
functional ion channels that are activated by temperature (threshold, ∼47C), but not by capsaicin

Capsaicin receptor: TRPV1 a promiscuous TRP channel

SC Pingle, JA Matta, GP Ahern - … Receptor Potential (TRP) Channels, 2007 - Springer
… Rat taste-receptor cells express a TRPV1 splice variant that is constitutively active in the …
as the nonspecific salt taste receptor. A few other splice variants have been described but their …

The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat

JF Sanchez, JE Krause, DN Cortright - Neuroscience, 2001 - Elsevier
… VR1 5′ splice variant RNA is expressed at levels 12 times … and that VR1 5′ splice variant
is expressed at low levels in … an N-terminal splice variant of the capsaicin receptor. Loss of …

The rat vanilloid receptor splice variant VR. 5′ sv blocks TRPV1 activation

H Eilers, SY Lee, CW Hau, A Logvinova… - …, 2007 - journals.lww.com
… Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal
domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem …

Vanilloid (capsaicin) receptors in health and disease

A Szallasi - American journal of clinical pathology, 2002 - academic.oup.com
… Molecular cloning of an N-terminal splice variant of the capsaicin receptor: loss of N-terminal
domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem. …

Effect of single-nucleotide polymorphisms in TRPV1 on burning pain and capsaicin sensitivity in Japanese adults

N Okamoto, M Okumura, O Tadokoro… - Molecular …, 2018 - journals.sagepub.com
receptor for both heat and capsaicin, have been previously examined, and the heat and
capsaicin … and the introns in the vicinity of the splice sites; however, there are many unanalyzed …

Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant

W Tian, Y Fu, DH Wang… - American Journal of …, 2006 - journals.physiology.org
… of potentially novel splice variants in the kidney. We report a novel rat TRPV1 splice variant,
TRPV1 … Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-…

Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel

I Nagy, D Friston, JS Valente, JVT Perez… - Capsaicin as a …, 2014 - Springer
… These include the presence of different splice variants of TRPV1, post-translational
modification (eg specific phosphorylation sites), or tetrameric combinations of TRP channels (see …