Alternative splicing in the C‐terminus of CaV2.2 controls expression and gating of N‐type calcium channels

AJ Castiglioni, J Raingo… - The Journal of …, 2006 - Wiley Online Library
… induced by exposure to 500 nm capsaicin. A–C, lower panels … of Ca V 2.2 splice variants
isolated from other calcium currents, … regulates expression of postsynaptic receptors. A specific …

[PDF][PDF] TRPV1 (transient receptor potential cation channel, subfamily V, member 1)

M Nabissi, G Santoni - Atlas Genet Cytogenet Oncol Haematol, 2011 - researchgate.net
splice variants with relative 5' UTR length are described in table. The TRPV1 splice variant
(… but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). …

The tissue distribution and functional characterization of human VR1

DN Cortright, M Crandall, JF Sanchez, T Zou… - Biochemical and …, 2001 - Elsevier
… (9–11) and capsaicin-activated currents (12). Here we describe the cloning of the capsaicin
receptor (VR1) from a … sites based on the sequences of rat SIC and rat VR1 5 splice variant. …

The diversity in the vanilloid (TRPV) receptor family of ion channels

MJ Gunthorpe, CD Benham, A Randall… - Trends in pharmacological …, 2002 - cell.com
… Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal
domain suggests functional divergence among capsaicin receptor subtypes. …

Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures

S Ständer, C Moormann, M Schumacher… - Experimental …, 2004 - Wiley Online Library
receptor family such as vanilloid receptor-like protein-1 (VRL-1), VRL-2, and vanilloid receptor
5′-splice variant … histamine receptor antagonists resulted in a reduction of the capsaicin-…

An N-terminal variant of Trpv1 channel is required for osmosensory transduction

RS Naeini, MF Witty, P Séguéla, CW Bourque - Nature neuroscience, 2006 - nature.com
… Here we show that SON neurons express an N-terminal splice variant of the transient
receptor potential vanilloid type-1 (Trpv1), also known as the capsaicin receptor, but not full-length …

The role of the capsaicin receptor TRPV1 and acid-sensing ion channels (ASICS) in proton sensitivity of subpopulations of primary nociceptive neurons in rats and …

A Leffler, B Mönter, M Koltzenburg - Neuroscience, 2006 - Elsevier
… and functional properties of the capsaicin receptor and acid-… Here, we asked how the capsaicin
receptor TRPV1 and acid-… showed that the majority of capsaicin-sensitive rat dorsal root …

[HTML][HTML] Capsaicin induces apoptosis in PC12 cells through ER stress

O Krizanova, I Steliarova, L Csaderova… - Oncology …, 2014 - spandidos-publications.com
… of the vanilloid family, binds to a receptor called the vanilloid receptor subtype 1 (TRPV1),
which … For example, it was shown that overexpression of a splice variant of RyR2 may trigger …

… of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1

JR Savidge, SP Ranasinghe, HP Rang - Neuroscience, 2001 - Elsevier
… and recombinant capsaicin receptors when activated by either heat or capsaicin by
imaging … is dependent on other factors or processes such as alternative splicing, post-translational …

TRPV1 genetics

R Dorfman, H Tsui, MW Salter… - … Receptor TRPV1 in Drug …, 2010 - Wiley Online Library
VARIANTS There are at least six different splice variants of the human trpv1 gene; four
variants … The variant channel was hyporesponsive to capsaicin at low doses (< 10 nM) but was …