Carboxyl-terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin-and heat-induced desensitization
… in activation by capsaicin and heat and that capsaicin and heat desensitize TRPV1 through
apparently distinct mechanisms, we hypothesized that capsaicin and heat desensitize …
apparently distinct mechanisms, we hypothesized that capsaicin and heat desensitize …
Complex regulation of TRPV1 by vanilloids
A Szallasi, PM Blumberg - TRP ion channel function in sensory …, 2007 - books.google.com
… , EA, and Bunnett, NW Protease activated receptor 2 sensitizes the capsaicin receptor transient
… receptor VR1 and VR1 5’splice variant RNA expression in rat. Neurosci. 107: 373, 2001. …
… receptor VR1 and VR1 5’splice variant RNA expression in rat. Neurosci. 107: 373, 2001. …
(608): Quantitative analysis of sodium channel expression in normal and painful human teeth
… domain is exposed and the cleaved receptors are activated. It is known … of capsaicin. This
suggests that PAR1 may be involved in … Additionally, our search reveals two splicing variants (…
suggests that PAR1 may be involved in … Additionally, our search reveals two splicing variants (…
Capsaicin indirectly regulates TRPA1 via the arachidonic acid cascade, resulting in TJ opening
Y Kanda, M Mukaiyama, Y Yamasaki… - Bioscience …, 2024 - academic.oup.com
… Capsaicin is thought to cause a series of biological effects by acting on the capsaicin receptor
… In MDCK II monolayers, PTGS1, which encodes COX1 and its splice variant COX3, were …
… In MDCK II monolayers, PTGS1, which encodes COX1 and its splice variant COX3, were …
The potential antitumor effects of capsaicin
I Díaz-Laviada, N Rodríguez-Henche - Capsaicin as a therapeutic …, 2014 - Springer
… However, the capsaicin-induced apoptotic effect at high doses is a receptor-independent
mechanism, as … The involvement of PPAR receptors in the capsaicin antitumor activity has been …
mechanism, as … The involvement of PPAR receptors in the capsaicin antitumor activity has been …
Transient receptor potential channels in pain and inflammation: therapeutic opportunities
MA Schumacher - Pain Practice, 2010 - Wiley Online Library
… , the capsaicin receptor, also known as transient receptor potential … splice variant subunit.
Although there is a reduction of keratinocyte and fibroblast growth in the presence of capsaicin (…
Although there is a reduction of keratinocyte and fibroblast growth in the presence of capsaicin (…
SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population
O Carreno, R Corominas… - American Journal of …, 2012 - Wiley Online Library
… TRPV1 was identified as the capsaicin receptor and is activated by noxious temperature, …
splicing enhancers or silencers, changing of splicing pattern or efficiency by disrupting splice …
splicing enhancers or silencers, changing of splicing pattern or efficiency by disrupting splice …
Future perspectives of capsaicin research
J Szolcsányi - Capsicum, 2003 - taylorfrancis.com
… The capsaicin receptor-encoding cDNA was identified by … other factors, including splice
variants, aggregation with other … varying responsiveness of the capsaicin receptor/ ion channel …
variants, aggregation with other … varying responsiveness of the capsaicin receptor/ ion channel …
Expression of vanilloid VR1 receptor in PC12 cells
A Someya, K Kunieda, N Akiyama… - Neurochemistry …, 2004 - Elsevier
… receptor subtype 1 (VR1), which is a nonselective cation channel with high Ca 2+ permeability.
Although VR1 and its splice variant … Axonal transport of VR1 capsaicin receptor mRNA in …
Although VR1 and its splice variant … Axonal transport of VR1 capsaicin receptor mRNA in …
Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation
JY Kim, EH Kim, SU Kim, TK Kwon, KS Choi - Carcinogenesis, 2010 - academic.oup.com
… Here, we show that subtoxic doses of capsaicin effectively … cells, cotreatment with capsaicin
and TRAIL efficiently restored … with capsaicin significantly upregulated DR5, a death receptor …
and TRAIL efficiently restored … with capsaicin significantly upregulated DR5, a death receptor …