[HTML][HTML] A retrospective study of stage I to IIIa lung adenocarcinoma after resection: What is the optimal adjuvant modality for patients with an EGFR mutation?

C Lv, C An, Q Feng, Y Ma, S Li, J Wang, J Zhang… - Clinical Lung Cancer, 2015 - Elsevier
… Another study revealed that in N2 patients with stage IIIa disease and EGFR mutation, the
observation group had even longer median DFS (49 vs. 30 months; P = .195) and OS (59 vs. …

[HTML][HTML] EGFR mutation impact on definitive concurrent chemoradiation therapy for inoperable stage III adenocarcinoma

K Tanaka, T Hida, Y Oya, T Oguri, T Yoshida… - Journal of Thoracic …, 2015 - Elsevier
… diagnosed as stage III adenocarcinoma without lymph node biopsies. The diagnosis of N
stage was clinically … In conclusion, concurrent CRT gave shorter PFS in EGFR-mutated stage III

[HTML][HTML] ADAURA: phase III, double-blind, randomized study of osimertinib versus placebo in EGFR mutation-positive early-stage NSCLC after complete surgical …

YL Wu, RS Herbst, H Mann, Y Rukazenkov, M Marotti… - Clinical lung cancer, 2018 - Elsevier
phase II and III trials of patients whose disease had progressed with an early-generation
EGFR-… In a phase III trial of patients with EGFR mutation-positive advanced NSCLC (FLAURA […

Adjuvant osimertinib for resected EGFR-mutated stage IB-IIIA non–small-cell lung cancer: updated results from the phase III randomized ADAURA trial

RS Herbst, YL Wu, T John, C Grohe… - Journal of Clinical …, 2023 - ascopubs.org
EGFR-TKI with demonstrated efficacy in NSCLC, including in the CNS. The primary DFS
analysis of the phase III … in patients with EGFR-mutated stage IB-IIIA NSCLC after complete …

EGFR mutations in early‐stage and advanced‐stage lung adenocarcinoma: Analysis based on large‐scale data from China

C Pi, CR Xu, M Zhang, X Peng, X Wei, X Gao… - Thoracic …, 2018 - Wiley Online Library
… Second, the number of patients who underwent EGFR mutation screening during the early
stages of their disease, especially stage IIA and IIB, was small, which may have affected our …

… plus cisplatin as adjuvant therapy in Chinese patients with stage IIIA EGFR mutation-positive non-small-cell lung cancer (EVAN): a randomised, open-label, phase 2 …

D Yue, S Xu, Q Wang, X Li, Y Shen, H Zhao… - The Lancet …, 2018 - thelancet.com
… with high-risk (ie, stage III) NSCLC, which is consistent with trials … stage IIIA NSCLC and
also suggests that EGFR TKI therapy could be an appropriate adjuvant therapy in EGFR mutation

… Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A Randomized Phase II Study

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… CTONG 1103 was a national, multicenter, open-label, phase II, randomized controlled trial
stage IIIA-N2 NSCLC with EGFR mutations in exon 19 or 21 (EMERGING); EGFR mutation

Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II-IIIA (N1-N2) EGFR-mutant NSCLC: final overall survival analysis of CTONG1104 phase III …

WZ Zhong, Q Wang, WM Mao, ST Xu, L Wu… - Journal of clinical …, 2021 - ascopubs.org
… improvement in DFS in patients with stage IB-IIIA EGFR-mutant NSCLC (HR, 0.20; … stage
II-IIIA (N1-N2) EGFR-mutant NSCLC may be changed from adjuvant therapy to adjuvant EGFR

Targeted treatment for unresectable EGFR mutation-positive stage III non-small cell lung cancer: Emerging evidence and future perspectives

T Kato, I Casarini, M Cobo, C Faivre-Finn… - Lung Cancer, 2023 - Elsevier
… unresectable EGFRm stage III NSCLC. We outline the rationale for investigating EGFR-TKI …
gaps and future challenges for treating patients with unresectable EGFRm stage III NSCLC. …

The impact of EGFR mutations on the incidence and survival of stages I to III NSCLC patients with subsequent brain metastasis

WY Chang, YL Wu, PL Su, SC Yang, CC Lin, WC Su - PloS one, 2018 - journals.plos.org
… 19 deletion (Del) tended to have a longer survival after BM than the non-EGFR 19 Del group
(… data suggested EGFR mutation to be one of the predictors for subsequent BM in stage I-III