… In this paper, we concentrate on two aspects of statistical prognosis. We discuss the ways
in which data from prognostic studies can be analysed so as to delineate the most useful …

… using a variety of statistical methodology and clinical inclusion criteria. A set of guidelines
for the conduct and reporting of phase III prognostic factor studies is proposed in Table I. …

… up-dated statistical methodology but also to point out the possible pitfalls when applying
these methods to prognostic factor studies. Statistical aspects of prognostic factor studies are …

… measurement, outcome measurement, adjustment for other prognostic factors, and statistical
analysis and reporting. Table 2 shows the signalling items within these domains to help …

… In this paper procedures to supplement standard analyses of prognostic factors will be …
factors in determining this outcome. Measures used to describe the relative importance of …

… A study would be considered to have low risk of bias if the statistical analysis is appropriate
for the data, statistical assumptions are satisfied, and all primary outcomes are reported. …

… selected rank statistics over the K factors. We define the maximally selected rank … the method
improves the assessment of prognostic factors with regression trees in clinical research and …

… For example, all of the 20 articles we assessed provided a statistical methods section in
their Methods; all 20 reported the total number of participants within their IPD; 15 of the 20 …

… We can now place the relative strengths of prognostic factors in this defined context.
previously noted in Figure 1A, the relative strength of a prognostic factor is indicated by the …

… studies to examine the variation in prognosis in relation to a single putative prognostic variable
of interest (also called a prognostic … the 40 studies had used a statistical method to derive …