… stem cell niche. We compare the differences and commonalities of different stem cell niches
… and functions of the stem cell niche and highlight important niche signals that are conserved …

… the most highly studied stem cell niches (Figure 2) by focusing on the physical contact
involved in niche organization as well as the diffusible factors involved in stem cell regulation. We …

… stem cells or other targets. The interplay between stem cells and their niche creates the
dynamic … necessary for sustaining tissues, and for the ultimate design of stem-cell therapeutics. …

… We provide in vivo evidence to show that a change in the niche size affects the number of
stem cells. BMP signalling through BMPRIA is an important component of this regulatory …

… stem cell is asked to function. In this Perspective, I review existing and emerging evidence
suggesting that the stem cell niche … discovery of novel stem cell regulatory mechanisms and …

… (or ‘niche’) directs their fate. The importance of the stem cell niche in regulating HSC function
was … Since then, it has become clear that not only HSCs but all somatic stem cells maintain …

… (two of the best characterized niches). By such comparison, we hope to provide some
common principles of stem cell niches that will be useful in other tissue stem cell niche studies. …

… and are increasingly recognized as components of stem cell niches, which are best defined
in … of hematopoietic cells, and how mesenchymal cells contribute to other stem cell niches. …

… of the niche in some stem cell systems. Like all other established cell lines, stem cells were
… little attention paid to the metabolic milieu of the niche in which they were grown or normally …

… In addition to the restraints imposed by niche cytoarchitecture, the neural stem cell niche is
under the influence of a complex array of diffusible molecular signaling molecules, including …