Effects of oxidative stress on mesenchymal stem cell biology

RA Denu, P Hematti - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
… Mesenchymal stromal/stem cells (MSCs) are multipotent stem cells present in most fetal …
oxidative stress in MSC biology, as their longevity and functions are affected by oxidative stress. …

Oxidative stress in stem cell aging

F Chen, Y Liu, NK Wong, J Xiao, KF So - Cell transplantation, 2017 - journals.sagepub.com
… features of stem cell aging biology, with an emphasis on the roles of oxidative stress in the
… Here, we summarize several key pathways contributing to oxidative stress-related stem cell

Pharmacological regulation of oxidative stress in stem cells

J Lee, YS Cho, H Jung, I Choi - Oxidative Medicine and Cellular …, 2018 - Wiley Online Library
… to develop protocols for regulating appropriate stem cell differentiation and maintenance
for … roles of oxidative stress in pluripotent stem cells (PSCs) and hematopoietic stem cells (HSCs…

Oxidative stress induces senescence in human mesenchymal stem cells

A Brandl, M Meyer, V Bechmann, M Nerlich… - Experimental cell …, 2011 - Elsevier
Cells from each donor were examined in 3 experimental groups: prolonged oxidative
stress, acute oxidative stress in young (1st passage) and old MSCs (high passage, reduced …

[HTML][HTML] ROS and oxidative stress in stem cells

A Cieślar-Pobuda, J Yue, HC Lee… - Oxidative Medicine …, 2017 - ncbi.nlm.nih.gov
… Since stem cells are considered as a promising tool in regenerative medicine, … stem cells
is maintained under oxidative stress and the role of ROS should be elucidated before stem cells

Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal

YL Guo, S Chakraborty, SS Rajan, R Wang… - Stem cells and …, 2010 - liebertpub.com
… Using well-established in vitro cell culture models that investigate H 2 O 2 -induced oxidative
stress, we examined the effects of H 2 O 2 -induced oxidative stress applied at different …

Human mesenchymal stem cells efficiently manage oxidative stress

A Valle-Prieto, PA Conget - Stem cells and development, 2010 - liebertpub.com
… The transplantation of mesenchymal stem cells (MSCs) proves to be useful to treat
pathologies in which tissue damage is linked to oxidative stress (OS). The aim of our work was to …

Role of oxidative stress in stem, cancer, and cancer stem cells

AA Dayem, HY Choi, JH Kim, SG Cho - Cancers, 2010 - mdpi.com
… Very little is known about the redox status in cancer stem cells [11]. Therefore, we will …
oxidative stress on cancer and stem cells, as understanding redox control in stem and cancer cells

[HTML][HTML] FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

Z Tothova, R Kollipara, BJ Huntly, BH Lee… - Cell, 2007 - cell.com
To understand the role of FoxO family members in hematopoiesis, we conditionally deleted
FoxO1, FoxO3, and FoxO4 in the adult hematopoietic system. FoxO-deficient mice exhibited …

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

K Ito, A Hirao, F Arai, S Matsuoka, K Takubo… - Nature, 2004 - nature.com
… Terc) deficiency, led to neural stem cell failure characterized by increased telomere erosion.
… not affect neural stem cells. To investigate roles of ATM on self-renewal of stem cells in detail…