Oxidative stress in normal hematopoietic stem cells and leukemia

A Samimi, H Kalantari, MZ Lorestani, R Shirzad, N Saki - Apmis, 2018 - Wiley Online Library
… drugs on oxidative stress pathways. By emphasizing the role of oxidative stress on stem
cells in the incidence of leukemia, this paper attempts to state and summarize this subject. …

Hsp20-engineered mesenchymal stem cells are resistant to oxidative stress via enhanced activation of Akt and increased secretion of growth factors

X Wang, T Zhao, W Huang, T Wang, J Qian, M Xu… - Stem …, 2009 - academic.oup.com
… Characterization of mesenchymal stem cells (MSCs) isolated … in MSCs in response to oxidative
stress, we treated MSCs with 200 … that Hsp20 may be instrumental during oxidative stress. …

Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy

JC Estrada, Y Torres, A Benguria, A Dopazo… - Cell death & …, 2013 - nature.com
… In most clinical trials, human mesenchymal stem cells (hMSCs) are expanded in vitro
before … stem cells is critical for their clinical use. However, the relationship between stem-cell

Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

L Wang, X Zeng, HD Ryoo, H Jasper - PLoS genetics, 2014 - journals.plos.org
… In this study, we identify a coordinated role of UPR ER and oxidative stress signaling in
regulating the proliferation of intestinal stem cells (ISCs). We find that the ER-stress responsive …

Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction

YT Chen, CK Sun, YC Lin, LT Chang, YL Chen… - Journal of translational …, 2011 - Springer
… We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs) protect the
kidney against oxidative stress and inflammatory stimuli in rat during renal IR injury. …

[HTML][HTML] Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation

Q Hu, P Khanna, BSE Wong, ZSL Heng… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… Reactive oxygen species (ROS) play important roles in fundamental cellular … of oxidative
stress on stem cell maintenance and neuronal differentiation in a human embryonic stem cell (…

Oxidative stress, bone marrow failure, and genome instability in hematopoietic stem cells

C Richardson, S Yan, CG Vestal - International journal of molecular …, 2015 - mdpi.com
… between phenotypes at the cellular level. This review summarizes work linking the ability
to regulate intracellular ROS to the hematopoietic stem cell phenotype, aging, and disease. …

Loss of ATM impairs proliferation of neural stem cells through oxidative stress-mediated p38 MAPK signaling

J Kim, PKY Wong - Stem cells, 2009 - academic.oup.com
… Even though oxidative stress has been implicated in the neurological … neural stem cell (NSC)
survival has remained elusive. In this study, we investigated the effects of oxidative stress

Oxidative stress-induced biomarkers for stem cell-based chemical screening

SR Yang, I Rahman, JE Trosko, KS Kang - Preventive Medicine, 2012 - Elsevier
… to detect cellular changes during self-renewal and differentiation of stem cells. This review
highlights the biomarker development to monitor oxidative stress response for stem cell-…

Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells

Y Wang, L Liu, SK Pazhanisamy, H Li, A Meng… - Free Radical Biology …, 2010 - Elsevier
… attributable to the induction of hematopoietic stem cell (HSC) senescence. However, the …
of chronic oxidative stress in HSCs was associated with sustained increases in oxidative DNA …