Soft material approach to induce oxidative stress in mesenchymal stem cells for functional tissue repair

H Yang, KT Nguyen, DT Leong, NS Tan… - ACS applied materials …, 2016 - ACS Publications
… are powerful tools to modulate the behaviors of stem cells. Herein, the use of fibronectin-…
the intracellular oxidative stress of human bone marrow derived mesenchymal stem cells (MSCs…

Lipopolysaccharides can protect mesenchymal stem cells (MSCs) from oxidative stress-induced apoptosis and enhance proliferation of MSCs via Toll-like receptor …

Z Wang, F Zhang, L Wang, Y Yao, Q Zhao… - Cell biology …, 2009 - Elsevier
Apoptosis of implanted mesenchymal stem cells (MSCs) limits the efficiency of MSC therapy.
Recent studies showed the ligands of Toll-like receptors (TLRs) could control the function of …

Exacerbation of oxidative stress-induced cell death and differentiation in induced pluripotent stem cells lacking heme oxygenase-1

CY Lin, CY Peng, TT Huang, ML Wu, YL Lai… - Stem Cells and …, 2012 - liebertpub.com
… By the loss-of-function approach using iPS-HO-1 –/– cells, our results demonstrate that a
lack of HO-1 renders iPS cells more prone to oxidative stress-induced cell death and …

Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells

R Farahzadi, B Valipour, E Fathi, S Pirmoradi… - Stem Cell Research & …, 2023 - Springer
Oxidative stress plays a pivotal role in a variety of anticancer strategies, such as radiation
therapy. Oxidative stress can affect all cell systems through a higher concentration of reactive …

Extracellular vesicles derived from bone marrow mesenchymal stem cells protect against experimental colitis via attenuating colon inflammation, oxidative stress and …

J Yang, XX Liu, H Fan, Q Tang, ZX Shou, DM Zuo… - PloS one, 2015 - journals.plos.org
… of BMSC-EVs on oxidative stress of TNBS colitis, we measured the levels of oxidants and
antioxidants in colon tissues. As showed in Fig 8, enhanced oxidative stress was evidenced by …

Research progress of extracellular vesicles and exosomes derived from mesenchymal stem cells in the treatment of oxidative stress-related diseases

W Zhang, T Wang, Y Xue, B Zhan, Z Lai… - Frontiers in …, 2023 - frontiersin.org
… Mesenchymal stem cell extracellular vesicles and exosomes … the related markers of oxidative
stress and inflammation in … and vascular injury induced by oxidative stress. The results of a …

Oxidative stress in mesenchymal stem cell senescence: regulation by coding and noncoding RNAs

R Vono, E Jover Garcia, G Spinetti… - Antioxidants & Redox …, 2018 - liebertpub.com
… This article reviews current understanding of the contribution of oxidative stress as a trigger
of modifications at DNA and RNA leading to MSC aging and senescence (Fig. 1). We also …

Oxidative stress and heme oxygenase‐1 regulated human mesenchymal stem cells differentiation

L Vanella, C Sanford Jr, DH Kim… - International journal …, 2012 - Wiley Online Library
… of osteoblastic cells [4, 13… oxidative injury remain unclear. However, targeting HO-1 expression
is a gateway to increasing osteoblast stem cell differentiation, decreasing oxidative stress

Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles

IM Pongrac, I Pavičić, M Milić… - International journal …, 2016 - Taylor & Francis
… We sought to investigate murine neural stem cells (NSCs) as important model system for
regenerative medicine. To reveal the possible mechanism of toxicity of SPIONs on NSCs, levels …

Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation

TL DeWeese, JM Shipman, NA Larrier… - Proceedings of the …, 1998 - National Acad Sciences
… To determine whether cells containing DNA mismatch repair enzyme gene defects were
tolerant to prolonged oxidative stress, we treated ES cells from mice carrying disrupted Msh2 …