… Wnt signaling in adult stem cell behavior, we furthermore focus on intestinal stem … stem
cells, we focus here on the role of Wnt/β-catenin signaling in the behavior of intestinal stem cells (…

… with the control of normal stem cell differentiation and how its … regulation of normal stem
cells and tumor cells within three … normal mammary stem cells and cancer stem cells (CSCs). …

… in normal and malignant stem cells. We centered this … of stem cells—embryonic stem
cells, hair follicle stem cells, and intestinal epithelial stem cells—in which the roles of Wnt/β-catenin …

… We show that the Wnt/β-catenin signaling pathway is required for self-… stem cells (HSC)
or more differentiated granulocyte-macrophage progenitors (GMP). Because the Wnt/β-catenin …

… We used the subgranular zone as a model stem cell niche, to evaluate the role of HIF-1α
in stem cell functions, because Wnt/β-catenin signalling has been identified as a positive …

… on cancer stem cells (CSCs), which co-opt stem cell properties 2 . For most tumours, the cellular
origin … Here we identify a population of cells in early epidermal tumours characterized by …

… addresses the role of β-catenin signaling in neural lineage commitment by ES cells. We find
… both β-catenin signaling and neural differentiation. However, overexpression of β-catenin is …

… through β-catenin has been ascribed a critical function in the stimulation of hematopoietic
stem cell self-renewal, whereas loss of β-catenin … activation of β-catenin blocked multilineage …

… implicated in stem cell (SC) biology, but little is known about how stabilized β-catenin functions
within native SC niches. We address this by defining the impact of β-catenin stabilization …

… show the localization of β-catenin at the Tert promoter to adult mouse stem cells and to human
cancer cell lines, supporting the notion that the regulation of Tert by β-catenin is a general …