Aldehyde dehydrogenase as a marker for stem cells

JS Moreb - Current stem cell research & therapy, 2008 - ingentaconnect.com
… Purification of viable cells with high ALDH activity has … of ALDH activity in normal and malignant
stem cell functions, and … We review the available tools that can impact ALDH activity and …

The role of human aldehyde dehydrogenase in normal and cancer stem cells

I Ma, AL Allan - Stem cell reviews and reports, 2011 - Springer
ALDH plays in normal stem cellsALDH isoenzymes and their properties, with a focus on
ALDH1A1 and ALDH3A1. Additionally, we will discuss how ALDH has been utilized in stem cell

[HTML][HTML] Aldehyde dehydrogenase 1A1 in stem cells and cancer

H Tomita, K Tanaka, T Tanaka, A Hara - Oncotarget, 2016 - ncbi.nlm.nih.gov
aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of
endogenous and exogenous aldehyde … tissue stem cells (SC) and cancer stem cells (CSC), …

Aldehyde dehydrogenases: not just markers, but functional regulators of stem cells

G Vassalli - Stem cells international, 2019 - Wiley Online Library
… In relation to stem cells, much emphasis has been placed on members of the ALDH1 family
of … ALDH not only may be used as a marker of stem cells but also may well regulate cellular

Aldehyde dehydrogenase: its role as a cancer stem cell marker comes down to the specific isoform

P Marcato, CA Dean, CA Giacomantonio, PWK Lee - Cell cycle, 2011 - Taylor & Francis
cells.Finally, the focus of this review, increased aldehydes dehydrogenase (ALDH) activity as
… hematopoietic stem cells, is now commonly used for the isolation of CSCs of many cancers.…

Aldehyde dehydrogenases and cancer stem cells

X Xu, S Chai, P Wang, C Zhang, Y Yang, Y Yang… - Cancer letters, 2015 - Elsevier
Aldehyde dehydrogenases (ALDHs), as essential regulators of aldehyde metabolism in the
human body, protect organisms from damage induced by active aldehydes. Given their roles …

[HTML][HTML] Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets

DW Clark, K Palle - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
… as the bulk tumor cells in order to achieve complete disease clearance. Aldehyde
dehydrogenases (ALDHs) are important for maintenance and differentiation of stem cells as well as …

Finding cancer stem cells: are aldehyde dehydrogenases fit for purpose?

MR Alison, NJ Guppy, SML Lim… - The Journal of …, 2010 - Wiley Online Library
Stem cell markers can be broadly categorized into molecular determinants of self-renewal, …
of recognizing cancer stem cells by virtue of high expression of aldehyde dehydrogenases (…

Aldehyde dehydrogenase: cancer and stem cells

AM Allahverdiyev, M Bagirova, ON Oztel… - …, 2012 - books.google.com
… above, ALDH is an important enzyme for cancer and stem cells. This chapter aims to represent
the important role of aldehyde dehydrogenases in stem cells, cancer stem cells, therapy …

Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations

S Ma, KW Chan, TKW Lee, KH Tang, JYH Wo… - Molecular Cancer …, 2008 - AACR
… their potential correlation to CD133 + cells and their prospective role as liver CSC markers.
Our results reveal, for the first time, that aldehyde dehydrogenase (ALDH), expressed along …