… to protect patients from adverse aortic events in clinical studies, … cells. In this review, we
summarize the patient iPSC-derived aortic cells that have been utilized to model aortic diseases …

… An aortic aneurysm (AA) is a silent but life-threatening disease that involves rupture… stem
cell research in regenerative medicine is remarkable. Stem cell is one of the most important cell …

… Induced, pluripotent stem cell models of proliferative diseases such as the one used here
should prove valuable in the search for candidate pathways and pharmaceutical agents. As a …

… In this study, we have shown that SCs are abundant in two other forms of aortic disease:
descending TAA and chronic TAD. Specifically, we found that there were significantly more …

… as a promising treatment for heart disease a decade ago 5 . Stem cells include embryonic
stem cells and adult stem cells. Embryonic stem cells, which are pluripotent stem cells, can be …

… The potent anti-inflammatory and immunosuppressive properties of MSCs have been
widely used as a cell-based therapy to treat various diseases like graft-versus-host disease, …

… stem cells (MSCs) are multipotent cells that can differentiate into a variety of cell types … of
the benefit of MSCs as cellular therapy for various inflammation-related diseases owing to their …

… Graphical summary demonstrating the utility of induced pluripotent stem cells (iPSC) in
understanding thoracic aortic disease (TAD) variants of unknown significance (VUS). iPSCs can …

… type of stem cell in the blood vessel wall, named multipotent vascular stem cells. Multipotent
… can differentiate into neural cells and mesenchymal stem cell-like cells that subsequently …

… stem cells have an important role in cardiovascular health and disease has been well
established, but the role of stem cells … in stem cell abundance when examining aortic tissue …