The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells

B Blum, O Bar-Nur, T Golan-Lev, N Benvenisty - Nature biotechnology, 2009 - nature.com
… Global gene expression analysis shows that survivin (BIRC5), an anti-apoptotic oncofetal
gene, is highly expressed in hES cells and teratomas but not in embryoid bodies. Genetic and …

Apoptosis, stem cells, and tissue regeneration

A Bergmann, H Steller - Science signaling, 2010 - science.org
stem and progenitor cells to aid in tissue regeneration. This Review summarizes some of the
key findings and discusses links to stem cellcell system made it possible to identify genes

Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium

CS Potten, JW Wilson, C Booth - Stem cells, 1997 - academic.oup.com
stem cells with preserved DNA integrity. In this review the incidence of apoptosis in the stem
cells … expression of a number of apoptosis regulating genes (eg p53, Bcl-2, bax) within these …

Apoptosis in normal and cancer stem cells

G Iannolo, C Conticello, L Memeo… - Critical reviews in oncology …, 2008 - Elsevier
stem cell biology, focusing on the apoptotic responses of haematopoietic and neural stem
cells … Depending on the number of DSBs, p53 can activate pro-apoptotic genes such as PUMA …

[HTML][HTML] Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

H Qin, T Yu, T Qing, Y Liu, Y Zhao, J Cai, J Li… - Journal of Biological …, 2007 - ASBMB
… its target genes has not been observed in other cell types, … apoptosis, we irradiated the H1
human embryonic stem cell line … h, the cells began to die; after 12 h, 67% of the irradiated cell

Electromagnetic fields affect transcript levels of apoptosis‐related genes in embryonic stem cell‐derived neural progenitor cells

T Nikolova, J Czyz, A Rolletschek… - The FASEB …, 2005 - Wiley Online Library
… study, EMF-induced effects on transcript levels of cell cycle regulatory and apoptosis-related
genes were detected in neural progenitor cells differentiated from wild-type ES cells. …

[HTML][HTML] Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells

D Duval, M Trouillas, C Thibault, D Dembelé… - Cell Death & …, 2006 - nature.com
… on ES cells upon LIF withdrawal, we found that PD169316 blocks cell apoptosis without …
overexpression of metallothionein 1 gene prevents apoptosis of early differentiated cells. …

[HTML][HTML] Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

G Liu, X Yuan, Z Zeng, P Tunici, H Ng, IR Abdulkadir… - Molecular cancer, 2006 - Springer
… such as MGMT, as well as genes related to inhibiting cell apoptosis on CD133 positive
cancer stem cells. Furthermore, we show that CD133 gene expression is significantly higher in …

Up-regulation of fas and fasL pro-apoptotic genes expression in type 1 diabetes patients after autologous haematopoietic stem cell transplantation

GLV De Oliveira, KCR Malmegrim… - Clinical & …, 2012 - academic.oup.com
… In this study, the apoptosis-related gene expression in T1D patients was evaluated before
… haematopoietic stem cell transplantation (HDI-AHSCT). We also correlated gene expression …

Stem cells: the intestinal stem cell as a paradigm

SP Bach, AG Renehan, CS Potten - Carcinogenesis, 2000 - academic.oup.com
… by reliable markers may aid the development of stem cell gene therapy for conditions such
as … indeed found a spontaneous apoptotic rate of ~5–10% in the stem cell region of the small …