The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells
… Global gene expression analysis shows that survivin (BIRC5), an anti-apoptotic oncofetal
gene, is highly expressed in hES cells and teratomas but not in embryoid bodies. Genetic and …
gene, is highly expressed in hES cells and teratomas but not in embryoid bodies. Genetic and …
Apoptosis, stem cells, and tissue regeneration
A Bergmann, H Steller - Science signaling, 2010 - science.org
… stem and progenitor cells to aid in tissue regeneration. This Review summarizes some of the
key findings and discusses links to stem cell … cell system made it possible to identify genes …
key findings and discusses links to stem cell … cell system made it possible to identify genes …
Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium
CS Potten, JW Wilson, C Booth - Stem cells, 1997 - academic.oup.com
… stem cells with preserved DNA integrity. In this review the incidence of apoptosis in the stem
cells … expression of a number of apoptosis regulating genes (eg p53, Bcl-2, bax) within these …
cells … expression of a number of apoptosis regulating genes (eg p53, Bcl-2, bax) within these …
Apoptosis in normal and cancer stem cells
… stem cell biology, focusing on the apoptotic responses of haematopoietic and neural stem
cells … Depending on the number of DSBs, p53 can activate pro-apoptotic genes such as PUMA …
cells … Depending on the number of DSBs, p53 can activate pro-apoptotic genes such as PUMA …
[HTML][HTML] Regulation of apoptosis and differentiation by p53 in human embryonic stem cells
… its target genes has not been observed in other cell types, … apoptosis, we irradiated the H1
human embryonic stem cell line … h, the cells began to die; after 12 h, 67% of the irradiated cell …
human embryonic stem cell line … h, the cells began to die; after 12 h, 67% of the irradiated cell …
Electromagnetic fields affect transcript levels of apoptosis‐related genes in embryonic stem cell‐derived neural progenitor cells
T Nikolova, J Czyz, A Rolletschek… - The FASEB …, 2005 - Wiley Online Library
… study, EMF-induced effects on transcript levels of cell cycle regulatory and apoptosis-related
genes were detected in neural progenitor cells differentiated from wild-type ES cells. …
genes were detected in neural progenitor cells differentiated from wild-type ES cells. …
[HTML][HTML] Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells
D Duval, M Trouillas, C Thibault, D Dembelé… - Cell Death & …, 2006 - nature.com
… on ES cells upon LIF withdrawal, we found that PD169316 blocks cell apoptosis without …
overexpression of metallothionein 1 gene prevents apoptosis of early differentiated cells. …
overexpression of metallothionein 1 gene prevents apoptosis of early differentiated cells. …
[HTML][HTML] Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
G Liu, X Yuan, Z Zeng, P Tunici, H Ng, IR Abdulkadir… - Molecular cancer, 2006 - Springer
… such as MGMT, as well as genes related to inhibiting cell apoptosis on CD133 positive
cancer stem cells. Furthermore, we show that CD133 gene expression is significantly higher in …
cancer stem cells. Furthermore, we show that CD133 gene expression is significantly higher in …
Up-regulation of fas and fasL pro-apoptotic genes expression in type 1 diabetes patients after autologous haematopoietic stem cell transplantation
GLV De Oliveira, KCR Malmegrim… - Clinical & …, 2012 - academic.oup.com
… In this study, the apoptosis-related gene expression in T1D patients was evaluated before
… haematopoietic stem cell transplantation (HDI-AHSCT). We also correlated gene expression …
… haematopoietic stem cell transplantation (HDI-AHSCT). We also correlated gene expression …
Stem cells: the intestinal stem cell as a paradigm
SP Bach, AG Renehan, CS Potten - Carcinogenesis, 2000 - academic.oup.com
… by reliable markers may aid the development of stem cell gene therapy for conditions such
as … indeed found a spontaneous apoptotic rate of ~5–10% in the stem cell region of the small …
as … indeed found a spontaneous apoptotic rate of ~5–10% in the stem cell region of the small …
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