[HTML][HTML] An efficient platform for astrocyte differentiation from human induced pluripotent stem cells

TCW Julia, M Wang, AA Pimenova, KR Bowles… - Stem cell reports, 2017 - cell.com
… rapid and robust method for the differentiation of highly pure populations of replicative
astrocytes from human induced pluripotent stem cells (hiPSCs), via a neural progenitor cell (NPC) …

[HTML][HTML] Astrocyte differentiation of human pluripotent stem cells: new tools for neurological disorder research

A Chandrasekaran, HX Avci, M Leist… - Frontiers in cellular …, 2016 - frontiersin.org
… on astrocytes continues, and our understanding of their disease-relevant cellular functions in
… Here, we review the role of astrocytes, compare their in vivo and in vitro differentiation, and …

Astrocyte-derived factors instruct differentiation of embryonic stem cells into neurons

T Nakayama, T Momoki-Soga, N Inoue - Neuroscience Research, 2003 - Elsevier
astrocyte-derived soluble factors are essential for differentiation of mouse ES cells into neural
stem cells … In cultivation under free-floating conditions in astrocyte-conditioned medium (…

Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes

L Emdad, SL D'Souza, HP Kothari… - Stem cells and …, 2012 - liebertpub.com
… neural progenitor cells can generate astrocytes during gliogenic … In the present study, we
compared the astrocyte differentiation … -1 differentiate to neuro-epithelial (NE) cells and then to …

Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively

MY Chang, H Son, YS Lee, SH Lee - Molecular and Cellular Neuroscience, 2003 - Elsevier
astrocytes in the differentiation of CNS stem cells. Using clonal density cultures of cortical
stem cells, … secreted by neurons and astrocytes markedly promoted differentiation of CNS stem

Rapid differentiation of astrocytes from human embryonic stem cells

JS Byun, CO Lee, M Oh, D Cha, WK Kim, KJ Oh… - Neuroscience …, 2020 - Elsevier
… This study increased the efficiency of astrocyte differentiationdifferentiation [7] and astrocyte
differentiation [1]. Both NPCs and astrocyte progenitor cells during astrocyte differentiation

[HTML][HTML] Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus

JM Encinas, TV Michurina, N Peunova, JH Park… - Cell stem cell, 2011 - cell.com
stem cells. We describe the life cycle of an adult neural stem cell and propose a “disposable
stem cell… age-related increase in astrocytes, the disappearance of hippocampal neural stem

Understanding astrocyte differentiation: Clinical relevance, technical challenges, and new opportunities in the omics era

M Lattke, F Guillemot - WIREs Mechanisms of Disease, 2022 - Wiley Online Library
… of adult astrocytes. … of astrocyte differentiation and maturation, due to biological and technical
challenges, including the high degree of similarity of astrocytes with neural stem cells and …

Induction of astrocyte differentiation by endothelial cells

H Mi, H Haeberle, BA Barres - Journal of Neuroscience, 2001 - Soc Neuroscience
… In addition to LIF, a number of other signals have been shown recently to promote
astrocyte differentiation from stem cells in culture, although it is not clear yet whether they also …

[HTML][HTML] A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

VM Jovanovic, C Weber, J Slamecka, S Ryu, PH Chu… - Stem Cell Reports, 2023 - cell.com
… of astrocytes from human pluripotent stem cells (hPSCs) is inefficient and cumbersome. Here,
we report controlled glial differentiation from … and in vitro differentiation. hPSCs were first …