Identification and functions of chondroitin sulfate in the milieu of neural stem cells

M Ida, T Shuo, K Hirano, Y Tokita, K Nakanishi… - Journal of Biological …, 2006 - ASBMB
… neural stem cells have been little studied. We found by immunohistochemistry … chondroitin
sulfate (CS) existed in the surroundings of nestin-positive cells or neural stem/progenitor cells

Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells

S Varghese, NS Hwang, AC Canver, P Theprungsirikul… - Matrix Biology, 2008 - Elsevier
… These interactions are partly mediated by cell surface … class of cell surface receptors
that mediate cellcell and cell–… aim to investigate the influence of chondroitin sulfate (CS)-based …

Chondroitin sulfate “wobble motifs” modulate maintenance and differentiation of neural stem cells and their progeny

A Purushothaman, K Sugahara, A Faissner - Journal of Biological …, 2012 - ASBMB
… renewal, proliferation, and differentiation is termed the “stem cell niche.” The neural stem
cell niche consists of restricted sets of cell types and contains a specialized microenvironment ( …

Chondroitin sulfate as a potential modulator of the stem cell niche in cornea

S Ashworth, J Harrington, GM Hammond… - Frontiers in Cell and …, 2021 - frontiersin.org
… derived-corneal epithelial cells. … a population of mesenchymal stem cells, termed corneal
stromal stem cells, in the extracellular matrix subjacent to the corneal epithelial stem cell niche (…

Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells

T Izumikawa, B Sato, H Kitagawa - Scientific reports, 2014 - nature.com
Chondroitin sulfate (CS) proteoglycans are present on the surfaces of virtually all cells and
… Studies have shown that heparan sulfate (HS) is essential for maintaining mouse embryonic …

Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells

S Sirko, A von Holst, A Wizenmann, M Gotz, A Faissner - 2007 - journals.biologists.com
… Although the local environment is known to regulate neural stem cell (NSC)… chondroitin
sulfates promote proliferation and self-renewal of early telencephalic stem/progenitor cells

Chondroitin sulfates are required for fibroblast growth factor-2-dependent proliferation and maintenance in neural stem cells and for epidermal growth factor …

S Sirko, A von Holst, A Weber, A Wizenmann… - Stem …, 2010 - academic.oup.com
… maintenance of neuron-generating neural stem/progenitor cells. Simultaneously, CS-GAGs …
of neural stem/progenitor cells. We conclude that neural stem/progenitor cell subpopulations …

Chondroitin sulfate glycosaminoglycan hydrogels create endogenous niches for neural stem cells

L Karumbaiah, SF Enam, AC Brown… - Bioconjugate …, 2015 - ACS Publications
… brain are self-renewing cells that are capable of supporting both … stem cells such as human
embryonic stem cells (hESCs) and differentiation resistant induced pluripotent stem cells (…

… multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates …

K Akita, A Von Holst, Y Furukawa, T Mikami… - Stem …, 2008 - academic.oup.com
… formation, we added defined, commercially available chondroitin sulfates to chlorate-treated
neurosphere-derived cells to rescue neural stem cell maintenance and self-renewal. At …

Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina

S Singhal, JM Lawrence, B Bhatia, JS Ellis… - Stem Cells, 2008 - academic.oup.com
… migration and integration of stem cells transplanted into the … role of chondroitin sulfate
proteoglycans (CSPGs) and microglia in the migration of human Müller glia with neural stem cell