Hematopoietic stem cell (HSC) populations change with aging, but the extent to which this
is caused by qualitative versus quantitative alterations in HSC subtypes is unclear. Using …

… of the transduced cells. Using clonal analysis, we show here that (i) the cells with the … culture
(more than 150 cell generations), (iii) keratinocyte stem cells integrate either one or multiple …

… 100 other stem cells, and … stem cells, as well as an analysis of the distribution of clone sizes.
At this dose =50% of the positive animals are expected to have more than one marked clone …

… cells residing within adult adipose tissue. In this study, we have demonstrated that the majority
of hADAS cell clones derived … , chondrogenic, and neuron-like cells (Table 3). This finding, …

… of disease at the time of analysis varied from 4 to 147 months. Clinical data of ten
patients studied by clonal analysis are given in Table I. Southern blot analysis. …

… Here we evaluated, by clonal analysis, the … corneal stem cells are located exclusively in
the limbus, fully confirming previous experiments performed by analyzing label-retaining cells in …

… cell genesis occurs from distinct lineage-restricted progenitors or from self-renewing and
multipotent neural stem cells in the … Clonal analysis identified multiple modes of RGL activation, …

… cells with a limited growth capacity were also located in P3 fragments. Clonal analysis was
not performed on cells … However, the clonal type of the colony-forming cells in that fragment …

… stem cell giving rise to a multipotent progenitor cell has been derived from the hematopoietic
system and is commonly proposed as a blueprint for the hierarchy of other stem cell …

… Using clonal analysis in combination with five-blood lineage (nm, B, T, E and P) analysis, we
previously … Our clonal analysis of HSC aging therefore questions the current dogma of HSC …