Prospect of stem cell conditioned medium in regenerative medicine

JA Pawitan - BioMed research international, 2014 - Wiley Online Library
Stem cell-derived conditioned medium has a promising … various methods to obtain stem
cell-derived conditioned medium (CM) … using keywords “stem cell” and “conditioned medium” or “…

Stem cells conditioned medium: a new approach to skin wound healing management

P Jayaraman, P Nathan, P Vasanthan… - Cell biology …, 2013 - Wiley Online Library
… harvested from cultured cells. Conditioned medium now serves as a new treatment modality
… described the possibility of using stem cells conditioned medium as a novel and promising …

Conditioned media derived from mesenchymal stem cell cultures: The next generation for regenerative medicine

TNA Gunawardena, MT Rahman… - Journal of tissue …, 2019 - Wiley Online Library
stem cells towards the affected organ, which in turn would differentiate to organ-specific cells
We hypothesize that the addition of conditioned media derived from mesenchymal stem cell

Bone marrow-derived mesenchymal stem cells: isolation, expansion, characterization, viral transduction, and production of conditioned medium

M Gnecchi, LG Melo - Stem cells in regenerative medicine, 2009 - Springer
… We also describe a method for preparation of conditioned and concentrated conditioned
medium from MSCs. The conditioned medium can be easily tested both in vitro and in vivo …

Stem cell-conditioned medium accelerates distraction osteogenesis through multiple regenerative mechanisms

Y Ando, K Matsubara, J Ishikawa, M Fujio, R Shohara… - Bone, 2014 - Elsevier
… Here we demonstrate that the local administration of serum-free conditioned medium from
human mesenchymal stem cells (MSC-CM) accelerated callus formation in the mouse H-DO …

Stem cell conditioned medium improves acute lung injury in mice: in vivo evidence for stem cell paracrine action

L Ionescu, RN Byrne, T van Haaften… - … -Lung Cellular and …, 2012 - journals.physiology.org
… In addition, since the use of MSCs as whole-cell therapy may hold some risks to the
patient (2, 38), we investigated the effects of MSC-derived conditioned medium (CdM) in LPS-…

Conditioned medium from human mesenchymal stromal cells: towards the clinical translation

G Sagaradze, O Grigorieva, P Nimiritsky… - International journal of …, 2019 - mdpi.com
… FGF2, a strong mitogenic and pro-migratory factor for fibroblasts, has the potential to
promote angiogenesis and to increase survival and proliferation of stem cells in vivo [59,60]. …

Efficacious and clinically relevant conditioned medium of human adipose-derived stem cells for therapeutic angiogenesis

SH Bhang, S Lee, JY Shin, TJ Lee, HK Jang, BS Kim - Molecular Therapy, 2014 - cell.com
… Using stem cellconditioned medium (CM) might be a viable alternative to … The stem
cell CM developed in this study will likely be an effective alternative to conventional stem cell

Conditioned media from mesenchymal stem cells enhanced bone regeneration in rat calvarial bone defects

M Osugi, W Katagiri, R Yoshimi, T Inukai… - … engineering part A, 2012 - liebertpub.com
… could affect cellular characteristics and behavior. This study investigated the effect of stem-cell-cultured
conditioned media on bone regeneration. Cultured conditioned media from …

Conditioned media from human adipose tissue‐derived mesenchymal stem cells and umbilical cord‐derived mesenchymal stem cells efficiently induced the apoptosis …

C Yang, D Lei, W Ouyang, J Ren, H Li… - BioMed research …, 2014 - Wiley Online Library
… We found (1) MSC conditioned media can significantly inhibit the … conditioned media from
human mesenchymal stem cells can efficiently induce apoptosis in U251 human glioma cell