… stem cells could be restricted by the gain of DNA methylation of self-renewal genes (preventing
the undifferentiated features of stem cells in adult somatic cells) and the DNA methylation…

… the function of embryonic stem cells and adult stem cells (such as haematopoietic stem
cells, neural stem cells and germline stem cells), and changes in DNA methylation patterns are …

… In this review, we will give an overview of the existing methods for studying DNA methylation,
and review the key DNA methylation studies specific to ESCs, with an emphasis on reports …

… DNA methylation profiles To investigate the dynamics of DNA methylation in pluripotent
stem cells, we examined 5 ESC lines (HUESCs) [23], [24], 22 iPSC lines, their parent cells and …

… be reflected in multipotent progenitor and stem cell pools. To this end, we investigated the
DNA methylation profiles of cultured mesenchymal stromal/stem cells (MSC) derived from the …

… DNA methylation during in vivo differentiation remain underexplored. Here we report high-resolution
DNA methylation maps of adult stem … DNA methylation changes were locus specific …

… cellular differentiation and homeostasis. During development, different cell types acquire
distinct DNA methylation … For most genes, the pattern of DNA methylation is identical on both …

… Embryonic stem cells (ESCs) provide an ideal model system to address this issue because
… Finally, we found that DNA methylation plays a key role in maintaining these metastable …

… evade replicative senescence, whereas other primary cells lose their … DNA methylation
(SA-DNAm) changes. Here, we investigate SA-DNAm changes in mesenchymal stromal cells (…

… the only form of DNA methylation in mammalian genomes. Here we identify N 6 -methyladenine
as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a …