… associated with aging rather than cell specific epigenetic differences. This approach identified
a … Studies have examined the epigenome of multiple adult stem cells from young and old …

… , immortalized cell lines or induced pluripotent stem cell (… ultimately determine the difference
between cell types. In principle… reproducible cell type-specific epigenetic differences – which …

… Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to
human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we …

… It is the objective of this review to provide a comprehensive overview of the current
knowledge on the instability of the genome and epigenome of human pluripotent stem cells (hPSCs) …

… the cell nucleus. However, an experimental system that allows simultaneous visualization
of the dynamics of the epigenomic state and nuclear reorganization during cell differentiation …

… stem cells (mESCs) and primed epiblast stem cells (mEpiSCs) represent successive snapshots
of pluripotency during embryogenesis. Using transcriptomic and epigenomic … differences …

… By contrast, impaired cell fate commitment of adult stem cells … The epigenomic landscape
affects cellular differentiation by … , which could highlight the differences between in vitro and in …

… These methods measure the epigenomic differences among individual cells within a …
plasticity of epigenomic states within a cell population, such as among individual stem cells that …

… cells, particularly the epigenomic features that may functionally distinguish leukemia stem
cells (… Given the differences in global H3K4 and H3K79 methylation that distinguish c-kit + …

… Of note, however, our results differ from those of Melzner et al… in order to destabilize the
epigenome. By analogy to the … the epigenome of somatic stem cells may reprogram these cells to …