Allogeneic mesenchymal stem cells inhibited T follicular helper cell generation in rheumatoid arthritis

R Liu, X Li, Z Zhang, M Zhou, Y Sun, D Su, X Feng… - Scientific reports, 2015 - nature.com
… Recently, T follicular helper (Tfh) cells have emerged as a new T helper lineage specialized
in the assistance of B cells during the germinal center (GC) reactions in secondary lymphoid …

Bone marrow-derived mesenchymal stem cells inhibit T follicular helper cell in lupus-prone mice

X Yang, J Yang, X Li, W Ma, H Zou - Lupus, 2018 - journals.sagepub.com
… to limit over-activation of B cells in SLE. Mesenchymal stem cells (MSCs) are pluripotent
stem cells with the ability to differentiate into different cell lineages. MSCs are originally isolated …

Mesenchymal stem cell modulates T follicular helper cell to induce immunotolerance of islet allograft

J Guan, ZY Zhang, ZQ Zhou, H Li, DN Tong… - Transplantation …, 2015 - Elsevier
stem cells were able to protect the islet allograft by regulating the follicular helper T cells. …
The T follicular helper cell (Tfh) is an effector T cell that represents CD4 + CXCR5 + . It …

Infusion of human bone marrow-derived mesenchymal stem cells alleviates autoimmune nephritis in a lupus model by suppressing follicular helper T-cell …

E Jang, M Jeong, S Kim, K Jang, BK Kang… - Cell …, 2016 - journals.sagepub.com
… + T cells to enter the developmental program of a helper T (Th) cell subset, named follicular
helper T (Tfh) cells… These precursors of Tfh cells migrate into B-cell follicles via their CXCR5 …

Follicular helper T cells

CG Vinuesa, MA Linterman, D Yu… - Annual review of …, 2016 - annualreviews.org
cells to help B cells produce antibodies (40–42). CXCR5 is a chemokine receptor promoting
B and T cell migration toward B cell folliclesfollicular helper T cells, abbreviated as Tfh cells

New insights into the differentiation and function of T follicular helper cells

C King - Nature Reviews Immunology, 2009 - nature.com
… T follicular helper (T FH ) cells are a specialized subset of CD4 + T helper (T H ) cells that are
found in the B cell follicle … T FH cells provide help to B cells through the provision of soluble …

Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sjögren's syndrome through the …

R Liu, D Su, M Zhou, X Feng, X Li, L Sun - Rheumatology, 2015 - academic.oup.com
… The aim of this study was to investigate the effect of umbilical cord mesenchymal stem
cells (UC-MSCs) on circulating T follicular helper (cTfh) cells in primary SS (pSS) patients. …

The regulation and role of T follicular helper cells in immunity

EK Deenick, CS Ma - Immunology, 2011 - Wiley Online Library
cells were named follicular B helper T cells, now more commonly known as T follicular helper
(Tfh) cells. … of these cells, now considered a distinct T helper (Th) cell lineage that can arise …

Human Umbilical Cord Mesenchymal Stem Cells Inhibit T Follicular Helper Cell Expansion through the Activation of iNOS in Lupus-Prone B6.MRL-Faslpr Mice

Z Zhang, R Feng, L Niu, S Huang, W Deng… - Cell …, 2017 - journals.sagepub.com
… Mesenchymal stem cells (MSCs) are pluripotent stem cells with a wide array of
immunomodulatory effects on T and B lymphocytes, natural killer (NK) cells, and antigen-presenting …

[HTML][HTML] T follicular helper cell differentiation, function, and roles in disease

S Crotty - Immunity, 2014 - cell.com
… There has been a great deal of recent activity in the study of T follicular helper (Tfh) cells.
While the first evidence of Tfh cells was reported in human lymphoid tissue more than a decade …