[HTML][HTML] Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

MH Chin, MJ Mason, W Xie, S Volinia, M Singer… - Cell stem cell, 2009 - cell.com
… indistinguishable from embryonic stem cells (ESCs). A study of gene expression profiles of
… embryonic counterparts, a recurrent gene expression signature appears in iPSCs regardless …

Understanding development and stem cells using single cell-based analyses of gene expression

P Kumar, Y Tan, P Cahan - Development, 2017 - journals.biologists.com
… Here, we review how single-cell RNA sequencing has provided key … stem cell biology,
emphasizing the analytical approaches that are specific to studying gene expression in single cells

The profile of gene expression of human marrow mesenchymal stem cells

WA Silva Jr, DT Covas, RA Panepucci… - Stem …, 2003 - academic.oup.com
… in stem cells. This study reports the profile of gene expression in MSCs and identifies the
important contribution of extracellular protein products, adhesion molecules, cell motility, TGF-β …

Stem cell gene expression programs influence clinical outcome in human leukemia

K Eppert, K Takenaka, ER Lechman, L Waldron… - Nature medicine, 2011 - nature.com
… that high expression of stem cell expression signatures directly predicts patient survival in
cytogenetically normal AML and, therefore, that variation in stem cell expression programs …

Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors

JM Sperger, X Chen, JS Draper… - Proceedings of the …, 2003 - National Acad Sciences
gene expression patterns of seminoma, EC, and ES cells to be distinct but closely related,
and the EC and ES expression … are expressed in common between seminoma and EC cells, …

[HTML][HTML] Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells

Z Ghosh, KD Wilson, Y Wu, S Hu, T Quertermous… - PloS one, 2010 - journals.plos.org
… compared to hESCs, allowing us to specify core sets of donor genes that continue to be
expressed in each hiPSC line. We report that residual gene expression of the donor cell type …

Gene expression heterogeneities in embryonic stem cell populations: origin and function

AM Arias, JM Brickman - Current opinion in cell biology, 2011 - Elsevier
stem or progenitor cell activity. Here we discuss the relevance of heterogeneities in gene
expression to stem cell … Our discussion will be focused on Embryonic Stem (ES) cells, as they …

[HTML][HTML] Lab-specific gene expression signatures in pluripotent stem cells

AM Newman, JB Cooper - Cell stem cell, 2010 - cell.com
… the genetic homogeneity of human pluripotent stem cells and … between gene expression
signatures of pluripotent stem cells and … gene sets that positively correlate with lab-specific gene

Gene expression in human embryonic stem cell lines: unique molecular signature

B Bhattacharya, T Miura, R Brandenberger, J Mejido… - Blood, 2004 - ashpublications.org
stem cell populations reveals that while stem cells may use similar overall strategies to maintain
a stem cell … develop distinct molecular signatures for other stem cell populations as well. …

Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia

AJ Gentles, SK Plevritis, R Majeti, AA Alizadeh - Jama, 2010 - jamanetwork.com
stem cell model has been studied in solid tumors in addition to leukemia. Investigation of gene
expression in human breast cancer stem cells … of the cancer stem cell model in these solid …