Concise review: genomic stability of human induced pluripotent stem cells
K Martins‐Taylor, RH Xu - Stem cells, 2012 - academic.oup.com
… genomic stability of all analyzed hESC and hiPSC lines under identical culture conditions).
Moreover, the results of a genomic stability … genomic stability of various pluripotent cell lines. …
Moreover, the results of a genomic stability … genomic stability of various pluripotent cell lines. …
[HTML][HTML] Stem cells: the pursuit of genomic stability
SP Wyles, EB Brandt, TJ Nelson - International journal of molecular …, 2014 - mdpi.com
… In the promising era of stem cell research and therapy, ensuring genomic stability of stem
cells remains one of the highest priorities prior to clinical translation. In this review, we provide …
cells remains one of the highest priorities prior to clinical translation. In this review, we provide …
Genomic stability testing of pluripotent stem cells
E McIntire, S Taapken, K Leonhard… - … protocols in stem cell …, 2020 - Wiley Online Library
Pluripotent stem cell (PSC) cultures are subjected to selective pressures that can result in
acquisition and expansion of recurrent genetic abnormalities at any time. These recurrent …
acquisition and expansion of recurrent genetic abnormalities at any time. These recurrent …
Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells
TS Li, E Marbán - Stem cells, 2010 - academic.oup.com
… genomic stability in cardiac and embryonic stem cells. Karyotypic abnormalities in primary
human cardiac stem cells … in cardiac stem cells and in human embryonic stem cells revealed a …
human cardiac stem cells … in cardiac stem cells and in human embryonic stem cells revealed a …
Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells
K Naka, T Muraguchi, T Hoshii… - Antioxidants & redox …, 2008 - liebertpub.com
… on several intrinsic (cell-autonomous) and extrinsic (non–cell-… ) and disruptions of genomic
stability can impair HSC functions. … the maintenance of genomic stability affect HSC functions. …
stability can impair HSC functions. … the maintenance of genomic stability affect HSC functions. …
Genomic instability in stem cells: the basic issues
EA Prieto González, KH Haider - Stem cells: from potential to promise, 2021 - Springer
… pluripotent stem cells (iPSCs), mesenchymal stem cells (… of the in vitro manipulated stem
cells are determined by the … that influence the genomic stability of stem cells thus impeding the …
cells are determined by the … that influence the genomic stability of stem cells thus impeding the …
Concise review: genomic instability in human stem cells: current status and future challenges
… Also, it remains to be clarified the acceptable threshold number of passages able to grant
the maintenance of genomic stability, or at least, able to guarantee that despite any lesions …
the maintenance of genomic stability, or at least, able to guarantee that despite any lesions …
[HTML][HTML] Genomic instability in induced stem cells
CE Pasi, A Dereli-Öz, S Negrini, M Friedli… - Cell Death & …, 2011 - nature.com
… placed to develop more efficient protocols for inducing stem cells, care must be taken that
increased efficiency is not achieved at the expense of genomic stability. For example, c-Myc …
increased efficiency is not achieved at the expense of genomic stability. For example, c-Myc …
Genome stability of programmed stem cell products
U Martin - Advanced drug delivery reviews, 2017 - Elsevier
… Oxygen concentration is another parameter found to influence genomic stability of stem
cells. … Quantification of DNA damage in cardiac stem cells and in human ESCs revealed a …
cells. … Quantification of DNA damage in cardiac stem cells and in human ESCs revealed a …
Genomic stability in stem cells
I Riz, RG Hawley - Regulatory networks in stem cells, 2009 - Springer
… the most significant mutagens in stem cells, when elevated, activate … stem cell differentiation.
Based on studies performed primarily on hematopoietic stem cells and embryonic stem cells…
Based on studies performed primarily on hematopoietic stem cells and embryonic stem cells…
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