Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes

M Arabpour, A Saghazadeh, N Rezaei - International …, 2021 - Elsevier
Macrophage polarization is important for tissue regeneration … exosomes promote M1 to M2
polarization and increase anti-… and their functions in M2 macrophage polarization, which is …

[HTML][HTML] Advances in the regulation of macrophage polarization by mesenchymal stem cells and implications for ALI/ARDS treatment

C Liu, K Xiao, L Xie - Frontiers in Immunology, 2022 - frontiersin.org
… MSCs can regulate the balance of M1/M2 macrophage polarization to improve the … MSCs
regulate macrophage polarization and the signaling pathways associated with polarization. …

[HTML][HTML] Mechanism of mesenchymal stem cells in spinal cord injury repair through macrophage polarization

N An, J Yang, H Wang, S Sun, H Wu, L Li, M Li - Cell & bioscience, 2021 - Springer
… In this review, we summarize the influence of macrophage polarization on … macrophage
polarization. We hope that the data highlighted in this review may provide guidance for stem cell-…

[HTML][HTML] Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration

J Liu, B Chen, J Bao, Y Zhang, L Lei, F Yan - Stem cell research & therapy, 2019 - Springer
… dynamic changes of macrophage polarization after PDLSC transplantation. We found that
the early increased M2 polarization of macrophages by stem cell transplantation may account …

Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization

C Lo Sicco, D Reverberi, C Balbi, V Ulivi… - Stem cells …, 2017 - academic.oup.com
macrophage polarization, we began characterizing the interactions of EVs with recipient
cells… whether EV treatment could influence macrophage polarization from M1 to M2 phenotype …

Mesenchymal stem cells promote macrophage polarization toward M2b-like cells

G Kudlik, B Hegyi, Á Czibula, É Monostori… - Experimental cell …, 2016 - Elsevier
stem or stromal cells (MSCs) act on different components of the immune response including
macrophages … may modify the effect of MΦ polarization upon an inductive environment using …

… derived from pro‐inflammatory bone marrow‐derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage polarization

R Xu, F Zhang, R Chai, W Zhou, M Hu… - Journal of cellular …, 2019 - Wiley Online Library
stem cells (BMSCs) and their secreted exosomes promote macrophage polarization and …
mediate inflammation and myocardial injury via macrophage polarization after MI. Here, we …

[HTML][HTML] Human umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis

TH Shin, HS Kim, TW Kang, BC Lee, HY Lee… - Cell death & …, 2016 - nature.com
… -derived mesenchymal stem cells elicit polarization of m2 macrophages and … stem cell-derived
interleukin 1 receptor antagonist promotes macrophage polarization and inhibits B cell

A biomimetic hierarchical nanointerface orchestrates macrophage polarization and mesenchymal stem cell recruitment to promote endogenous bone regeneration

SS Jin, DQ He, D Luo, Y Wang, M Yu, B Guan, Y Fu… - ACS …, 2019 - ACS Publications
… To further explore whether and how HIMC induces M2 macrophage polarization, we … -1-derived
macrophages (Figure 3A). CD163, Arg-1, and IL-10 were defined as M2 macrophage

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles alter disease outcomes via endorsement of macrophage polarization

J Wang, J Xia, R Huang, Y Hu, J Fan, Q Shu… - Stem Cell Research & …, 2020 - Springer
… that MSC-EVs reduce M1 polarization and/or promote M2 polarization in a variety of settings…
of macrophage polarization and roles of MSC-EV-induced macrophage polarization in the …