Nonviable human pre-implantation embryos as a source of stem cells for research and potential therapy

M Alikani, S Munné - Stem Cell Reviews, 2005 - Springer
… Human embryonic stem cells are derived from the inner cell mass of the human blastocyst.
Presumably normal (frozen/thawed) human preimplantation embryos … for stem cell derivation. …

Self-correction of chromosomal abnormalities in human preimplantation embryos and embryonic stem cells

M Bazrgar, H Gourabi, MR Valojerdi… - Stem cells and …, 2013 - liebertpub.com
… Aneuploid embryos have been used for the derivation of normal embryonic stem cell (ESC) …
This review addresses aneuploidies in human preimplantation embryos and human ESCs …

[HTML][HTML] Isolation of epiblast stem cells from preimplantation mouse embryos

FJ Najm, JG Chenoweth, PD Anderson, JH Nadeau… - Cell stem cell, 2011 - cell.com
stem cell states to one another remains largely undefined. We have shown that mouse
embryonic stem (ES) cells and epiblast stem cells … -implantation embryos respectively. Human ES …

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

L Yan, M Yang, H Guo, L Yang, J Wu, R Li… - Nature structural & …, 2013 - nature.com
… Here we apply single-cell RNA sequencing (RNA-Seq) analysis to 124 individual cells
from human preimplantation embryos and human embryonic stem cells (hESCs) at different …

Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells

J Van Blerkom - Reproductive biomedicine online, 2008 - Elsevier
… , preimplantation stage embryos and possibly, stem cells. The notion of microzonation, in
which mitochondria may be functionally compartmentalized within the somatic cell cytoplasm (…

POU5F1 isoforms show different expression patterns in human embryonic stem cells and preimplantation embryos

G Cauffman, I Liebaers, A Van Steirteghem… - Stem …, 2006 - academic.oup.com
… Human Preimplantation Embryos. Human preimplantation embryos were obtained for
research at our Center for Reproductive Medicine with the couples' informed consent and the …

Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

A Pfeifer, M Ikawa, Y Dayn… - Proceedings of the …, 2002 - National Acad Sciences
… gene transfer into ES cells and preimplantation embryos, we used … cell lines, including
hematopoietic stem cells (12, 20–22). (iii) To achieve transgene expression not only in ES cells

In vitro establishment of expanded-potential stem cells from mouse pre-implantation embryos or embryonic stem cells

J Yang, DJ Ryan, G Lan, X Zou, P Liu - Nature Protocols, 2019 - nature.com
… be possible to establish stem cell lines with features of pre-implantation embryos from
even … to extra-embryonic lineages, we propose that stem cells with similarity to pre-implantation

[HTML][HTML] The naive state of human pluripotent stem cells: a synthesis of stem cell and preimplantation embryo transcriptome analyses

K Huang, T Maruyama, G Fan - Cell stem cell, 2014 - cell.com
… networks in naive pluripotent stem cells (PSCs) with preimplantation embryos. While gene
… data sets, different sources of human stem cells display high degrees of variation, partly …

Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens

JK Henderson, JS Draper, HS Baillie, S Fishel… - Stem …, 2002 - academic.oup.com
… (EC) cells, the stem cells of teratocarcinomas and the presumed malignant counterparts …
embryo-derived ES cells [3–, 6]. Murine ES cells closely resemble cells of the late inner cell