Maximum efficacy of mesenchymal stem cells in rat model of renal ischemia-reperfusion injury: renal artery administration with optimal numbers

J Cai, X Yu, R Xu, Y Fang, X Qian, S Liu, J Teng… - PloS one, 2014 - journals.plos.org
… by low rates of cell engraftment after … administration through renal artery can enhance
the migration and therapeutic potential of mesenchymal stem cells (MSCs) in ischemic kidney. …

Efficiency of endovenous versus arterial administration of mesenchymal stem cells for ischemia-reperfusion–induced renal dysfunction in rats

W Zhuo, L Liao, Y Fu, T Xu, W Wu, S Yang… - Transplantation …, 2013 - Elsevier
… We hypothesized that site-directed delivery of MSCs to the injured kidney via the renal
artery might be more effective than systemic delivery to alleviate I/R-induced injury. …

Adipose tissue‐derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis

A Eirin, XY Zhu, JD Krier, H Tang, KL Jordan… - Stem …, 2012 - academic.oup.com
renal arterial patency and at the same time improving the regenerative capacity of the poststenotic
kidney using cell‐… rate in the kidney 4 weeks after intra‐arterial administration was 13.1…

Stem cell delivery to kidney via minimally invasive ultrasound-guided renal artery injection in mice

M Zaw Thin, O Ogunlade, J Comenge, PS Patrick… - Scientific reports, 2020 - nature.com
… -guided renal artery injection was developed to improve stem cell delivery to the kidney without
… distribution of administered mesenchymal stem cells in acute kidney injury. Am J Physiol …

Mesenchymal stem cells and chronic renal artery stenosis

EB Oliveira-Sales, MA Boim - … Journal of Physiology-Renal …, 2016 - journals.physiology.org
stem cells (MSC) in an experimental animal model of renovascular hypertension known as 2
kidney… Oliveira-Sales and coworkers (24) demonstrated that MSC, administered through the …

Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosis

B Ebrahimi, A Eirin, Z Li, XY Zhu, X Zhang, A Lerman… - PloS one, 2013 - journals.plos.org
… Revascularization of the stenotic renal artery alone does not restore renalstem cells (MSC)
to percutaneous transluminal renal angioplasty (PTRA) can restore stenotic-kidney

Comparison of the effects of mesenchymal stem cells with their extracellular vesicles on the treatment of kidney damage induced by chronic renal artery stenosis

CSRA Ishiy, MS Ormanji, E Maquigussa… - Stem Cells …, 2020 - Wiley Online Library
cells were administered to an additional group of stenotic rats six weeks after renal artery
groups were established according to the period after ASC administration: 24 hours (n = 3), 48 …

… arterial administration of human umbilical cord-derived mesenchymal stem cells effectively preserved the residual renal function of diabetic kidney disease in rat

Y Yue, JN Yeh, JY Chiang, PH Sung, YL Chen… - Stem Cell Research & …, 2022 - Springer
renal artery was identified by visual observation. Next, the HUCDMSCs inside a 30# needle
were carefully and slowly injected into the renal artery … needle wound of renal artery until the …

… and effective route of administration for mesenchymal stem cell-based immunomodulation therapy in experimental kidney transplantation: endovenous or arterial?

S Zonta, M De Martino, G Bedino, G Piotti… - Transplantation …, 2010 - Elsevier
… the renal artery. A single dose of sodium heparin (1000 UI) was administered, and the kidney
was … The renal artery was excised with an aortic patch, the renal vein was cut proximal to its …

Localization and maintenance of engrafted mesenchymal stem cells administered via renal artery in kidneys with ischemia-reperfusion injury

Y Yamada, A Nakashima, S Doi, N Ishiuchi… - International journal of …, 2021 - mdpi.com
… following three different administration routes (tail vein, carotid artery, and renal artery).
They showed that MSCs administered through the renal artery could maintain renal function for …