[HTML][HTML] Stem cells in the treatment of renal fibrosis: a review of preclinical and clinical studies of renal fibrosis pathogenesis

Y Liu, YY Su, Q Yang, T Zhou - Stem Cell Research & Therapy, 2021 - Springer
… signaling pathways) of renal fibrosis, and the effect of stem cell therapy on renal fibrosis as
described in preclinical and clinical studies. We found that stem cells from various sources …

Mesenchymal stem cells in renal fibrosis: the flame of cytotherapy

Q Zhuang, R Ma, Y Yin, T Lan, M Yu… - Stem cells …, 2019 - Wiley Online Library
fibrotic process. According to the latest and overall literature … of diverse sources of MSCs on
renal fibrosis, assess their efficacy … novel ideas into the MSC cellular therapy of renal fibrosis. …

Arterially delivered mesenchymal stem cells prevent obstruction-induced renal fibrosis

H Asanuma, BA Vanderbrink, MT Campbell… - Journal of Surgical …, 2011 - Elsevier
… Male Sprague-Dawley rats underwent renal artery injection … the renal cortex analyzed for
evidence of stem cell infiltration, … (FSP+) staining, renal fibrosis (collagen content, Masson's …

Mesenchymal stem cells attenuate renal fibrosis through immune modulation and remodeling properties in a rat remnant kidney model

P Semedo, M Correa-Costa, M Antonio Cenedeze… - Stem …, 2009 - academic.oup.com
… improvement in renal function parameters after MSC treatment, we examined the renal
architecture and quantified the amount of fibrosis. The MSC-treated animals showed less fibrosis, …

Adipose-derived mesenchymal stem cells: a new tool for the treatment of renal fibrosis

Z Wang, D Sun - Stem Cells and Development, 2018 - liebertpub.com
… of renal fibrosis. In this review, we discuss the mechanisms involved in the treatment of
renal fibrosis with AMSCs and summarize the potential hazards that may exist in cell therapy. …

Injection of amniotic fluid stem cells delays progression of renal fibrosis

S Sedrakyan, S Da Sacco, A Milanesi… - Journal of the …, 2012 - journals.lww.com
… In conclusion, treatment with amniotic fluid stem cells may be beneficial in kidney diseases
characterized by progressive renal fibrosis. Stem cells, which are derived from several …

[HTML][HTML] Interferon-γ enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis

R Kanai, A Nakashima, S Doi, T Kimura, K Yoshida… - Scientific Reports, 2021 - nature.com
… , which induces further inflammation and fibrosis. Therefore, the inhibition of inflammation
is expected to ameliorate renal fibrosis. Mesenchymal stem cells (MSCs) isolated from various …

[HTML][HTML] Hypoxia-preconditioned mesenchymal stem cells prevent renal fibrosis and inflammation in ischemia-reperfusion rats

N Ishiuchi, A Nakashima, S Doi, K Yoshida… - Stem cell research & …, 2020 - Springer
… MSCs on renal fibrosis and … renal fibrosis and inflammation more significantly than rat 21%O
2 MSCs. Notably, human 1%O 2 MSCs (1%O 2 hMSCs) also attenuated renal fibrosis to the …

[HTML][HTML] Mesenchymal stem cells deliver exogenous microRNA-let7c via exosomes to attenuate renal fibrosis

B Wang, K Yao, BM Huuskes, HH Shen, J Zhuang… - Molecular therapy, 2016 - cell.com
… Using bioluminescence imaging in mice with unilateral ureteral obstruction (UUO), we
report that mesenchymal stem cells (MSCs), engineered to overexpress miRNA-let7c (miR-let7c-…

Serum-free medium enhances the immunosuppressive and antifibrotic abilities of mesenchymal stem cells utilized in experimental renal fibrosis

K Yoshida, A Nakashima, S Doi, T Ueno… - Stem cells …, 2018 - academic.oup.com
… This study showed that the serum-free medium for mesenchymal stem cells (MSCs) … cells,
in MSCs. Thus, MSCs cultured in serum-free conditions significantly ameliorate renal fibrosis