Stem cells and spinal cord injury repair

S Karimi-Abdolrezaee, E Eftekharpour - … of the Spine and Spinal Cord, 2012 - Springer
Regenerative Biology of the Spine and Spinal Cord, 2012Springer
Spinal cord injury (SCI) has remained a challenging area for scientists and clinicians due to
the adverse and complex nature of its pathobiology. To date, clinical therapies for
debilitating SCI are largely ineffective. However, emerging research evidence suggests that
repair of SCI can be promoted by stem cell-based therapies in regenerative medicine. Over
the past decade, therapeutic potential of different types of stem cells for the treatment of SCI
have been investigated in preclinical models. These studies have revealed multiple …
Abstract
Spinal cord injury (SCI) has remained a challenging area for scientists and clinicians due to the adverse and complex nature of its pathobiology. To date, clinical therapies for debilitating SCI are largely ineffective. However, emerging research evidence suggests that repair of SCI can be promoted by stem cell-based therapies in regenerative medicine. Over the past decade, therapeutic potential of different types of stem cells for the treatment of SCI have been investigated in preclinical models. These studies have revealed multiple beneficial roles by which stem cells can improve the outcomes of SCI. This chapter will summarize the recent advances in the application of stem cells in regenerative medicine for the repair of SCI.
Springer
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