[HTML][HTML] Understanding and targeting cancer stem cells: therapeutic implications and challenges

K Chen, Y Huang, J Chen - Acta Pharmacologica Sinica, 2013 - nature.com
… Normal stem cells and cancer stem cells appear to express … enable cancer stem cells to
resist current cancer therapies 25,… malignant stem cells can be determined by treatment of cells

Therapeutic implications of cancer stem cells

M Al-Hajj, MW Becker, M Wicha, I Weissman… - Current opinion in …, 2004 - Elsevier
… the cancer stem cell and its dysregulated self-renewal, our therapies for treating … implications
for the way we study, diagnose and treat cancer if the same populations of cancer cells are …

[HTML][HTML] Cancer stem cells: therapeutic implications and perspectives in cancer therapy

L Han, S Shi, T Gong, Z Zhang, X Sun - Acta Pharmaceutica Sinica B, 2013 - Elsevier
therapies (chemotherapy, radiotherapy) and the resistant mechanisms inherent in CSCs
and the micronvironment; and discuss the multiple therapeutic implications of targeting CSCs. …

[HTML][HTML] Differences and similarities between cancer and somatic stem cells: therapeutic implications

F Rossi, H Noren, R Jove, V Beljanski… - … cell research & therapy, 2020 - Springer
… Evidence has shown that cancer stem cells (CSCs), a sub-population of cells that share
many common characteristics with somatic stem cells (SSCs), contribute to this therapeutic

Side population and cancer stem cells: therapeutic implications

L Moserle, M Ghisi, A Amadori, S Indraccolo - Cancer letters, 2010 - Elsevier
… target of conventional therapies. Moreover, certain cytokines – such as IFN-α – appear to
modulate SP and stem cell functions, and this associates with remarkable therapeutic activity in …

[HTML][HTML] Oral cancer stem cells: Therapeutic implications and challenges

LA Shahoumi - Frontiers in Oral Health, 2021 - frontiersin.org
… suggests that therapeutic resistance and metastasis of cancer are mainly driven by a unique
subpopulation of tumor cells, termed cancer stem cells (CSCs), or cancer-initiating cells (…

[HTML][HTML] Neural stem cells of the subventricular zone as the origin of human glioblastoma stem cells. Therapeutic implications

ER Matarredona, AM Pastor - Frontiers in oncology, 2019 - frontiersin.org
Cell therapy can also be achieved via ICV administration. For instance, stem cells genetically
modified to release factors with antitumor effects have also been demonstrated to be …

Cancer stem cells: basic concepts and therapeutic implications

D Nassar, C Blanpain - Annual Review of Pathology …, 2016 - annualreviews.org
… subpopulations of cancer cells with increased renewal capacity and the ability to recapitulate
the heterogeneity found in primary tumors, which are referred to as cancer stem cells (CSCs…

Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-renewal
and differentiation with a broad tissue distribution. Initially described in bone marrow, …

Stem cells and burns: review and therapeutic implications

KL Butler, J Goverman, H Ma… - Journal of burn care …, 2010 - academic.oup.com
Stem cells, which enhance wound healing and counteract systemic inflammation, now offer
potential therapies for … seeks to illustrate applications of stem cell therapy to burn care and to …