Pluripotency inducing Yamanaka factors: role in stemness and chemoresistance of liver cancer
H Fatma, HR Siddique - Expert Review of Anticancer Therapy, 2021 - Taylor & Francis
… the role of OSKM in inducing pluripotency and stem cell-like … Yamanaka factors’ role in
stemness and chemoresistance of … of the major reasons for stemness and drug resistance and is …
stemness and chemoresistance of … of the major reasons for stemness and drug resistance and is …
Nicotine-induced ILF2 facilitates nuclear mRNA export of pluripotency factors to promote stemness and chemoresistance in human esophageal cancer
Y Li, M Wang, M Yang, Y Xiao, Y Jian, D Shi, X Chen… - Cancer Research, 2021 - AACR
This study defines a previously uncharacterized role of nicotine-regulated ILF2 in facilitating
nuclear mRNA export to promote cancer stemness, suggesting a potential therapeutic …
nuclear mRNA export to promote cancer stemness, suggesting a potential therapeutic …
Understanding the molecular mechanisms that regulate pancreatic cancer stem cell formation, stemness and chemoresistance: a brief overview
… Research indicates that CDK1 can directly influence the function of various pluripotency
factors such as Nanog, Sox2, and Oct4. The CDK1/cyclin A complex can phosphorylate Nanog, …
factors such as Nanog, Sox2, and Oct4. The CDK1/cyclin A complex can phosphorylate Nanog, …
[HTML][HTML] Chemotherapy-induced adenosine A2B receptor expression mediates epigenetic regulation of pluripotency factors and promotes breast cancer stemness
J Lan, G Wei, J Liu, F Yang, R Sun, H Lu - Theranostics, 2022 - ncbi.nlm.nih.gov
… factor FOXO3 activates expression of pluripotency factors in response to chemotherapy in
… in A2BR-induced pluripotency factor expression in response to chemotherapy, we searched …
… in A2BR-induced pluripotency factor expression in response to chemotherapy, we searched …
[HTML][HTML] The role of pluripotency factors to drive stemness in gastrointestinal cancer
M Müller, PC Hermann, S Liebau, C Weidgang… - Stem cell …, 2016 - Elsevier
… Various other OCT4-dependent mechanisms are thought to be involved in chemoresistance.
… an important role in tumor-associated chemoresistance and suggests that inhibition of the …
… an important role in tumor-associated chemoresistance and suggests that inhibition of the …
[HTML][HTML] CPEB1 mediates hepatocellular carcinoma cancer stemness and chemoresistance
M Xu, S Fang, J Song, M Chen, Q Zhang, Q Weng… - Cell death & …, 2018 - nature.com
… The mRNA expression and protein levels of the major pluripotency factors OCT4, NANOG,
SOX2 and LIN28 were all reduced in response to CPEB1 overexpression, significantly for …
SOX2 and LIN28 were all reduced in response to CPEB1 overexpression, significantly for …
Induction of cancer cell stemness by chemotherapy
X Hu, L Ghisolfi, AC Keates, J Zhang, S Xiang, D Lee… - Cell cycle, 2012 - Taylor & Francis
… We demonstrate that carboplatin can induce the self-renewal (spherogenesis) and
pluripotency (Sox2 and oct3/4 expression) of hepatocellular carcinoma (HCC) cells grown under …
pluripotency (Sox2 and oct3/4 expression) of hepatocellular carcinoma (HCC) cells grown under …
[HTML][HTML] Can stemness and chemoresistance be therapeutically targeted via signaling pathways in ovarian cancer?
L Roy, KD Cowden Dahl - Cancers, 2018 - mdpi.com
… pluripotency factors common in ovarian CSCs including OCT4, MYC, and ARID3B will provide
clarity for how cancer stemness … pathways involved in stemness and chemoresistance, we …
clarity for how cancer stemness … pathways involved in stemness and chemoresistance, we …
[HTML][HTML] Intrinsic and extrinsic factors impacting cancer stemness and tumor progression
A Ponomarev, Z Gilazieva, V Solovyeva, C Allegrucci… - Cancers, 2022 - mdpi.com
… Pluripotency factors and signaling pathways, which regulate and modulate cancer stemness
are … of stemness factor genes and increased drug resistance [134]. Finally, tumor necrosis …
are … of stemness factor genes and increased drug resistance [134]. Finally, tumor necrosis …
[HTML][HTML] Snail transcription factors as key regulators of chemoresistance, stemness and metastasis of ovarian cancer cells
M Kielbik, P Przygodzka, I Szulc-Kielbik… - Biochimica et Biophysica …, 2023 - Elsevier
… stem cells, significantly affects drug resistance acquisition. Transcription factors in the Snail
family have been implicated in ovarian cancer chemoresistance and metastasis. In this article…
family have been implicated in ovarian cancer chemoresistance and metastasis. In this article…
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