… are often influenced by stereochemistry and topographic … campaigns in chemical biology
and drug discovery. Here we … source of chemical information at the chemistry-biology interface. …

… with diverse biological behaviour, and that skeletal, substituent and stereochemical diversity
… At the highest structural resolutions available to molecular engineers in organic chemistry—…

… [36] This strategy involves three principal steps in the generation of libraries of skeletally
diverse and stereochemically defined compounds. Briefly, the build step involves the …

… chemistry and chemical biology, specifically the development of performance-diverse
libraries and the discovery … , appendage, and stereochemical diversity by greatly reducing the …

… functional groups with three-dimensional and stereochemical diversity. The complex three-…
diversity sites is essential and a highly challenging task. In the postgenomic chemical biology …

… creating new highly diverse and complex … chemical biology and drug discovery. This is due
primarily to improvement in the quality of chemical libraries, which are more stereochemically …

… His research programme is focused on synthetic chemistry and chemical biology. … exhibit
a high degree of structural diversity and an enhanced level of stereochemical complexity. …

… approaches to this stereochemical series were ineffective, we developed an effective
route involving tungsten-catalyzed alkynol cycloisomerization and discovered an intriguing …

… examine the impact of stereochemical diversity on the performance diversity of a model … of
stereochemical diversity as a possible general strategy to increase the performance diversity …

… diverse in scaffold, appendage, and stereochemistry. This library was screened for biological
activity and performance diversity … , stereochemistry, appendages, and chemical properties …