Sterile inflammation: sensing and reacting to damage

GY Chen, G Nuñez - Nature Reviews Immunology, 2010 - nature.com
… The sterile inflammation that ensues either resolves the initial insult or leads to disease.
Here, we review the triggers and receptor pathways that result in sterile inflammation and its …

Processes of sterile inflammation

H Shen, D Kreisel, DR Goldstein - The Journal of Immunology, 2013 - journals.aai.org
… activators both contribute to inflammation. In this … sterile inflammation, the triggers of these
conditions, signaling pathways of sterile inflammation, the implications of sterile inflammation, …

Sterile inflammation in the liver

P Kubes, WZ Mehal - Gastroenterology, 2012 - Elsevier
… Such sterile inflammation (SI) is a key process in drug-induced liver injury, nonalcoholic
steatohepatitis, and alcoholic steatohepatitis and is a major determinant of fibrosis and …

Molecular determinants of sterile inflammation

H Kono, A Onda, T Yanagida - Current opinion in immunology, 2014 - Elsevier
inflammation in sterile cell death, our understanding of the mechanism underlying this
inflammatory … responsible for mediating the inflammatory responses to sterile cell death, whereas …

[HTML][HTML] IL-1 family cytokines trigger sterile inflammatory disease

JR Lukens, JM Gross, TD Kanneganti - Frontiers in immunology, 2012 - frontiersin.org
… to define the inflammatory processes that are … of inflammation in sterile settings. Over the
past decade non-communicable chronic diseases that are potentiated by sterile inflammation

The sterile inflammatory response

KL Rock, E Latz, F Ontiveros… - Annual review of …, 2009 - annualreviews.org
… of this, sterile inflammation underlies the pathogenesis of a number of diseases. Although
there have been major advances in our understanding of how microbes trigger inflammation, …

[HTML][HTML] Role of sterile inflammation in fatty liver diseases

Y Chen, MN Yousaf, WZ Mehal - Liver Research, 2018 - Elsevier
Sterile inflammation is a ubiquitous response of tissues to stress and injury, and occurs to a
high degree in the liver. This results in high levels of tissue damage after development of the …

Inflammasome priming in sterile inflammatory disease

MN Patel, RG Carroll, S Galván-Peña, EL Mills… - Trends in molecular …, 2017 - cell.com
disease, and neuroinflammatory disorders. Indeed, many chronic inflammatory diseases
a view to chronic and also monogenic inflammatory diseases that are sterile in nature. We also …

The essential roles of Toll-like receptor signaling pathways in sterile inflammatory diseases

Q Lin, M Li, D Fang, J Fang, SB Su - International immunopharmacology, 2011 - Elsevier
… in the pathogenesis of sterile inflammation-related diseases may provide novel targets for …
knowledge about the role of TLRs in the pathogenic process of sterile inflammatory diseases. …

Mechanistic differences leading to infectious and sterile inflammation

F Behnia, S Sheller, R Menon - American journal of …, 2016 - Wiley Online Library
… ongoing work that document generation of sterile inflammation, substantiates the need for a
… produce sterile and infectious inflammation from human fetal membranes. Inflammation and …