… Sterile inflammation in the absence of pathogens can be … mechanism of sterile inflammation
is necroinflammation, where … [3] that contribute to inflammation-resolving pathways [4]. …

… Necroinflammation is associated with the release of damage-associated molecular …
necroinflammation can be crucial in developing strategies for the treatment of sterile inflammatory …

… Conversely, mice lacking Nlrp3, or molecules involved in inflammasome assembly, document
the deleterious effect of NLRP3 inflammasome activation in sterile inflammation models (…

… In stressful pathological situations, in which reactive oxygen species (ROS) are produced
in excess, OSEs accumulate and bind to PRRs to promote sterile inflammation, a typical …

… The relevance of our question is supported by the fact that sterile inflammation is induced in
… and RAMPs, in triggering inflammation during sterile inflammation is not widely investigated. …

… once intracellular and thus hidden from the immune system, can activate a variety of
immune cells thereby triggering inflammation, a process referred to as “necroinflammation” [43]. …

… In this review, the authors focus on the role of cell death and sterile inflammatory pathways
as well as the self-perpetuating deleterious cycle they may trigger as novel therapeutic …

… Similar to the necroinflammatory injury pattern in APAP intoxication, cholestatic liver injury …
in hepatocytes, and is associated with subsequent sterile inflammatory response [38,39]. In a …

… a critical component of inflammation, beyond the function of necroptosis [42, 43]. RIPK3-deficient
mice display enhanced protection against ischemic injury and sterile sepsis models via …

… inflammation remains an area of unexpected discoveries. The last decade unraveled the
molecular mechanisms of sterile inflammation… of kidney injury–related inflammation. In contrast, …