Disruption of the steroid metabolome in fish caused by exposure to the environmental estrogen 17α-ethinylestradiol
AM Flores-Valverde, J Horwood… - Environmental science & …, 2010 - ACS Publications
… steroid metabolome in animal tissues, allowing an investigation on the effect of estrogen
exposure a range of sex steroids … EE2 exposure on the steroid metabolome of sexually mature …
exposure a range of sex steroids … EE2 exposure on the steroid metabolome of sexually mature …
Responses in the crucian carp (Carassius auratus) exposed to environmentally relevant concentration of 17α-Ethinylestradiol based on metabolomics
X Zhou, Y Li, H Li, Z Yang, C Zuo - Ecotoxicology and Environmental Safety, 2019 - Elsevier
… Crucian carp were exposed to EE2 at environmentally … of the physiological endpoints, steroid
hormones, and metabolome. The … However, the mechanisms of estrogen-induced gonadal …
hormones, and metabolome. The … However, the mechanisms of estrogen-induced gonadal …
Methodology for Profiling the Steroid Metabolome in Animal Tissues Using Ultraperformance Liquid Chromatography− Electrospray-Time-of-Flight Mass Spectrometry
AM Flores-Valverde, EM Hill - Analytical chemistry, 2008 - ACS Publications
… in liver or testes, but ovarian extracts caused ion supression of estrogens. A comparison of
the steroid metabolome of the ovaries and testes using partial least-squares discrimination …
the steroid metabolome of the ovaries and testes using partial least-squares discrimination …
Microbial degradation of steroid sex hormones: implications for environmental and ecological studies
… Another example of interrogating environmental hormone degradation is using the 13 C-metabolomic
approach to identify major oestrogen degradation pathways in river waters. The …
approach to identify major oestrogen degradation pathways in river waters. The …
[HTML][HTML] The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and …
TV Nguyen, JM Reuter, NW Gaikwad… - Translational …, 2017 - nature.com
… exposures to ovarian steroids. To test this, we used a steroid-based metabolomics platform to
… /P4 sensitivity) were confirmed by ovarian steroid manipulation. The main goal of this study …
… /P4 sensitivity) were confirmed by ovarian steroid manipulation. The main goal of this study …
Using NMR metabolomics to identify responses of an environmental estrogen in blood plasma of fish
LM Samuelsson, L Förlin, G Karlsson… - Aquatic toxicology, 2006 - Elsevier
… metabolomics to compare blood plasma and plasma lipid extracts from rainbow trout exposed
to the synthetic contraceptive estrogen … knowledge of the effects of estrogens on fish. This …
to the synthetic contraceptive estrogen … knowledge of the effects of estrogens on fish. This …
Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol
… We report on the characterisation of stickleback responses to the model xenoestrogen
ethinyl-estradiol (EE 2 ), employing transcriptomics, metabolomics, and classical biomarkers such …
ethinyl-estradiol (EE 2 ), employing transcriptomics, metabolomics, and classical biomarkers such …
Metabolomic Response of Human Embryonic Stem Cell–Derived Germ-like Cells After Exposure to Steroid Hormones
… the metabolomic response of the synthetic estrogen, ethinyl … metabolomic profiling of GLCs
is a useful analytical tool in investigating the biochemical fluxes following exposure to steroid …
is a useful analytical tool in investigating the biochemical fluxes following exposure to steroid …
Ultra performance liquid chromatography-tandem mass spectrometry method for profiling of steroid metabolome in human tissue
NW Gaikwad - Analytical chemistry, 2013 - ACS Publications
… Overall presence of all major classes of steroids as well as estrogen derivatives was … of
steroid metabolome (Figure 1) composed of androgens, corticosteroids, progestogens, estrogens…
steroid metabolome (Figure 1) composed of androgens, corticosteroids, progestogens, estrogens…
Exposure to estrogenic mixtures results in tissue-specific alterations to the metabolome of oysters
… environmentally relevant mixtures of estrogens at levels representative of receiving waters on
the metabolome … Oysters were exposed to a “low” and a “high” mixture of (xeno) estrogens (…
the metabolome … Oysters were exposed to a “low” and a “high” mixture of (xeno) estrogens (…
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