Posttraumatic stress disorder: the role of medial prefrontal cortex and amygdala

M Koenigs, J Grafman - The Neuroscientist, 2009 - journals.sagepub.com
Posttraumatic stress disorder (PTSD) is characterized by recurrent distressing memories of
an emotionally traumatic event. In this review, the authors present neuroscientific data …

[HTML][HTML] The effects of stress exposure on prefrontal cortex: Translating basic research into successful treatments for post-traumatic stress disorder

AFT Arnsten, MA Raskind, FB Taylor, DF Connor - Neurobiology of stress, 2015 - Elsevier
… the stress response in animals has led to successful new treatments for Post-Traumatic Stress
Disorder … Basic research has found that high levels of catecholamine release during stress

The role of the amygdala and the ventromedial prefrontal cortex in emotional regulation: implications for post-traumatic stress disorder

DG Andrewes, LM Jenkins - Neuropsychology review, 2019 - Springer
… role of the ventromedial prefrontal cortex (vmPFC) … prefrontal cortex (vmPFC) and the distinct
role of two of its subcomponents, the rostral anterior cingulate cortex and orbitofrontal cortex

Functional connectivity of the prefrontal cortex and the amygdala in posttraumatic stress disorder

A Gilboa, AY Shalev, L Laor, H Lester, Y Louzoun… - Biological …, 2004 - Elsevier
BACKGROUND: Persistent, intrusive re-experiencing in posttraumatic stress disorder (PTSD)
is commonly construed as a failure of cingulate inhibition (ie, extinction) over a …

Thinner prefrontal cortex in veterans with posttraumatic stress disorder

E Geuze, HGM Westenberg, A Heinecke, CS de Kloet… - Neuroimage, 2008 - Elsevier
… Due to technical limitations of the cortical thickness algorithm, which performed less
accurately in the inferior temporal lobe, and medial prefrontal cortex, we only examined cortical

Measures of prefrontal system dysfunction in posttraumatic stress disorder

KC Koenen, KL Driver, M Oscar-Berman, J Wolfe… - Brain and …, 2001 - Elsevier
… pattern of prefrontal and limbic abnormalities. First, deficits on DR implicate abnormalities of
the dorsolateral prefrontal cortex (eg, … of memory disorders to posttraumatic stress disorder. …

Dorsolateral prefrontal cortex activation during emotional anticipation and neuropsychological performance in posttraumatic stress disorder

RL Aupperle, CB Allard, EM Grimes… - Archives of general …, 2012 - jamanetwork.com
stress disorder (PTSD) symptom severity related to less differential activation for anticipation
of negative (ANI) − positive (API) images in the bilateral dorsolateral prefrontal cortex (dlPFC…

A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder

LM Shin, CI Wright, PA Cannistraro… - Archives of general …, 2005 - jamanetwork.com
… studies have demonstrated exaggerated amygdala responses and diminished medial
prefrontal cortex responses during the symptomatic state in posttraumatic stress disorder (PTSD). …

[HTML][HTML] Neuroimaging research in posttraumatic stress disorder–Focus on amygdala, hippocampus and prefrontal cortex

N Henigsberg, P Kalember, ZK Petrović… - Progress in Neuro …, 2019 - Elsevier
prefrontal cortex, as these are the brain regions postulated by the core research to play a
prominent role in the pathophysiology of post-traumatic stress disorder… traumatic stress disorder

Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder

JD Bremner, RB Innis, SM Southwick… - American Journal of …, 2000 - Am Psychiatric Assoc
… the prefrontal cortex, the specific area of the prefrontal cortex implicated … prefrontal cortex
play in PTSD, although the role of specific subregions of this area in symptoms of this disorder