[HTML][HTML] Using phenomic analysis of photosynthetic function for abiotic stress response gene discovery

T Rungrat, M Awlia, T Brown, R Cheng… - The Arabidopsis Book …, 2016 - ncbi.nlm.nih.gov
… In addition, chlorophyll fluorescence has also been used to study abiotic stress responses
such as salt stress, drought and high light stress (Tsugane et al., 1999; Stepien and Johnson, …

Discovery and function of a general core hormetic stress response in E. coli induced by sublethal concentrations of antibiotics

A Mathieu, S Fleurier, A Frenoy, J Dairou, MF Bredeche… - Cell reports, 2016 - cell.com
… other stressors induce the same set of responses, we propose that it constitutes a general
core hormetic stress response. It is plausible that this response plays an important role in the …

Functional genomics in plant abiotic stress responses and tolerance: From gene discovery to complex regulatory networks and their application in breeding

K Shinozaki, K Yamaguchi-Shinozaki - Proceedings of the Japan …, 2022 - jstage.jst.go.jp
… in gene expression and signal transduction of stress responses. In addition to these proteins…
to function in the regulation of stress responses. Names and functions of genes for stress-…

Genomewide discovery of DNA polymorphisms in rice cultivars with contrasting drought and salinity stress response and their functional relevance

M Jain, KC Moharana, R Shankar… - Plant Biotechnology …, 2014 - Wiley Online Library
… conserved functional domains, were identified. The data presented in this study provide
functional … for high-throughput genotyping and molecular breeding for abiotic stress traits in rice. …

From Hans Selye's discovery of biological stress to the identification of corticotropin‐releasing factor signaling pathways: implication in stress‐related functional bowel …

Y Taché, S Brunnhuber - Annals of the New York Academy of …, 2008 - Wiley Online Library
… axis limb of the stress response. The peptide … response to stress, 13 the known biological
actions of CRF expanded quickly far beyond the neuroendocrine component of stress response

Functional linkage between genes that regulate osmotic stress responses and multidrug resistance transporters: challenges and opportunities for antibiotic discovery

BE Cohen - Antimicrobial agents and chemotherapy, 2014 - Am Soc Microbiol
… This is a basic principle of cellular function, … stress responses and MDR transporters will
help to identify novel strategies and targets to overcome the current stalemate in drug discovery. …

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
discovery of the Keap1-Nrf2-ARE pathway in later years. The experimentally identified functional
… prone to diseases in response to xenobiotics and oxidative stress as a consequence of …

The hypoxic inducible stress response as a target for cancer drug discovery

SJ Welsh, MY Koh, G Powis - Seminars in oncology, 2006 - Elsevier
… The response to the stress of hypoxia is mediated in large part by the hypoxia inducible
factor-1 (HIF-1) transcription factor that increases the expression of a variety of genes that allow …

The integrated stress response: From mechanism to disease

M Costa-Mattioli, P Walter - Science, 2020 - science.org
… and circuits to determine their function. From a medical perspective… Finally, discovery and
mechanistic understanding of additional … the regulation of mitochondrial function. Mitochondrial …

Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways

LP O'Reilly, JA Benson, EE Cummings… - … on Drug Discovery, 2014 - Taylor & Francis
… The IIS pathway appears to be a master regulator of the cellular stress response and
plays a role in modulating proteostasis by regulating HSR, UPR, proteasome function and …