The biological limitations of transcriptomics in elucidating stress and stress responses
ME Feder, JC Walser - Journal of evolutionary biology, 2005 - academic.oup.com
… undergoing environmental stress. In evolutionary analyses of stress, mRNA abundance is
often … examines the adequacy of mRNA abundance as a proxy for protein activity, fitness and …
often … examines the adequacy of mRNA abundance as a proxy for protein activity, fitness and …
Co-expression network analyses identify functional modules associated with development and stress response in Gossypium arboreum
Q You, L Zhang, X Yi, K Zhang, D Yao, X Zhang… - Scientific reports, 2016 - nature.com
… or modules in the regulatory mechanisms of important agronomic traits, especially growth
and stress response. … Q-RT-PCR and mRNA-seq results. The Q-RT-PCR results matched the …
and stress response. … Q-RT-PCR and mRNA-seq results. The Q-RT-PCR results matched the …
Integrated analysis of small RNA, transcriptome, and degradome sequencing reveals the water-deficit and heat stress response network in durum wheat
… in the molecular mechanism underlying stress tolerance (eg, … include modules like miR167
and ARF (auxin response factors)… of miRNA-mRNA modules between stress-tolerant and -…
and ARF (auxin response factors)… of miRNA-mRNA modules between stress-tolerant and -…
Connecting genes, coexpression modules, and molecular signatures to environmental stress phenotypes in plants
… To relate patterns of genome-wide mRNA expression to … stress specific responses such
as heat and UV-B. At the same time, our results illustrate the complexity of the stress response …
as heat and UV-B. At the same time, our results illustrate the complexity of the stress response …
Long non‐coding RNAs coordinate cellular responses to stress
SC Lakhotia - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
… sequences provides elegant modules for adaptability to … and, therefore, most studies dealing
with cell stress response … of mRNA from nucleus to cytoplasm under conditions of stress.76 …
with cell stress response … of mRNA from nucleus to cytoplasm under conditions of stress.76 …
ZBP1 regulates mRNA stability during cellular stress
N Stöhr, M Lederer, C Reinke, S Meyer… - The Journal of cell …, 2006 - rupress.org
… mRNAs to SGs is nonspecific, the stabilization of mRNAs during cellular stress requires specific
protein–mRNA … turnover of its target mRNAs during the integrated stress response (ISR). …
protein–mRNA … turnover of its target mRNAs during the integrated stress response (ISR). …
Treatment-associated mRNA co-expression changes in monocytes of patients with posttraumatic stress disorder
R Kumsta, JCS Zang, EM Hummel, S Müller… - Frontiers in …, 2023 - frontiersin.org
… So far, research on etiology implicated both, the endocrine stress response … module
showed-together with the pink module-the highest module significance scores for therapy response …
showed-together with the pink module-the highest module significance scores for therapy response …
Predictive modeling of genome-wide mRNA expression: from modules to molecules
HJ Bussemaker, BC Foat… - Annu. Rev. Biophys …, 2007 - annualreviews.org
… of module-based methods uses only mRNA expression data as input. Their distinguishing
feature is that they use the mRNA … the expression level of the modules. Here again, expression …
feature is that they use the mRNA … the expression level of the modules. Here again, expression …
The MazF-regulon: a toolbox for the post-transcriptional stress response in Escherichia coli
M Sauert, MT Wolfinger, O Vesper… - Nucleic Acids …, 2016 - academic.oup.com
… When cells encounter stress the toxin-antitoxin (TA) module … mRNAs as well as modification
of the translational machinery, we hypothesized that this post-transcriptional stress response …
of the translational machinery, we hypothesized that this post-transcriptional stress response …
Tudor staphylococcal nuclease links formation of stress granules and processing bodies with mRNA catabolism in Arabidopsis
… The N-terminal tandem repeat of four SN domains was sufficient for the targeting of TSN
to SGs and for protecting root cells from death during the stress response, while the C-terminal …
to SGs and for protecting root cells from death during the stress response, while the C-terminal …