… , such as autophagy, apoptosis, formation of stress granules, and innate immunity response.
… the ISR regulating viral replication and how viruses antagonize this cellular stress response …

… Viral proteins that promote S phase can activate the DDR as an oncogenic stress response.
The small DNA tumor virus–encoded proteins SV40 T antigen, human papillomavirus (HPV) …

Viral infection triggers activation of the integrated stress response (ISR). In response to viral
double-stranded RNA (dsRNA), RNA-activated protein kinase (PKR) phosphorylates the …

… in virus infection, focusing on both pro-viral and anti-viral host responses using a select group
of viruses. … viral protein translation and form intracellular stress granules that enhance anti-…

… Genes regulated by these miRNAs operate in distinct metabolic pathways, suggesting
that host reaction to viral synergy does not employ only genes involved in stress response. …

… the working mechanism of this other stress response pathway antagonist, we treated MERS-…
group of previously identified viral dsRNA-binding antagonists of stress response and IFN-α/…

… Although phosphorylation of mTOR was detected in this study and likely has an effect on
translation, it appears that subversion of PI3K/Akt signaling is important to antagonize virus-…

… replication, and this may lead to virus-induced mitochondrial stress and mtDNA release. … ,
and to understand whether these viruses have evolved strategies to antagonize their functions. …

… We demonstrate that AcP10 differs in its mode of action from all other viral ISR antagonists
described so far and counteracts the ISR at its core by acting as a competitive inhibitor of the p…

… Both the pathways and their responses have matured and expanded in vertebrates, where
these two stress response systems and their major transcription factors control stress in …