Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson's disease

K Fuxe, LF Agnati, K Jacobsen, J Hillion, M Canals… - Neurology, 2003 - AAN Enterprises
… glutamate 5 receptors (mGluR5) have also recently been demonstrated in HEK-293 cells
and rat striatal membrane preparations. The A 2A /mGluR5 receptor heteromer may account for …

Looking for the role of cannabinoid receptor heteromers in striatal function

S Ferré, SR Goldberg, C Lluis, R Franco - Neuropharmacology, 2009 - Elsevier
… We recently analyzed the role of receptor heteromers in the “striatal spine module”, a … now
analyze the possible functional significance of CB 1 receptor heteromers in striatal function. …

Adenosine receptor heteromers and their integrative role in striatal function

S Ferré, F Ciruela, C Quiroz, R Luján… - The Scientific World …, 2007 - Wiley Online Library
… By analyzing the functional role of adenosine receptor heteromers, … receptors cannot be
considered as single functional units anymore. Heteromerization of neurotransmitter receptors

Heteromerization of dopaminergic receptors in the brain: Pharmacological implications

D Misganaw - Pharmacological Research, 2021 - Elsevier
functional interaction between these two receptors [23]. In conclusion, D 2R -D 4.2R and
D 2R -D 4.4R heteroreceptor complexes exist in the striatum … also activate D 4 receptors [79]. …

Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance

R Maggio, G Aloisi, E Silvano, M Rossi… - Parkinsonism & related …, 2009 - Elsevier
Heterodimerization of dopamine receptors has been shown for both the D 1 /D 5 and D 2 /D
3 /D 4 receptor … and adenosine A 1 receptors; D 2 or D 3 and adenosine A 2 receptors; and D …

Dimerization of dopamine D1 and D3 receptors in the regulation of striatal function

C Fiorentini, C Busi, PF Spano, C Missale - Current opinion in …, 2010 - Elsevier
receptor heteromers and for a synergistic intramembrane D1–D3 receptor cross-talk in
transfected cells and striatal … From a functional point of view this interaction results in D3 receptor-…

A2A/D2 receptor heteromerization in a model of Parkinson's disease. Focus on striatal aminoacidergic signaling

L Ferraro, S Beggiato, MC Tomasini, K Fuxe… - Brain research, 2012 - Elsevier
… In the central nervous system (CNS) the receptorreceptor interactions have been studied …
receptors containing receptor mosaics (RM, higher-order receptor heteromers) in the striatum

Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function

S Ferré, C Quiroz, M Orru, X Guitart… - Frontiers in …, 2011 - frontiersin.org
… Finally, striatal A 2A Rs are also localized presynaptically, in cortico-striatal glutamatergic …
These presynaptic A 2A Rs heteromerize with A 1 receptors (A 1 Rs) and their activation …

Adenosine–cannabinoid receptor interactions. Implications for striatal function

S Ferré, C Lluís, Z Justinova, C Quiroz… - British journal of …, 2010 - Wiley Online Library
… a variety of heteromers of A 2A , CB 1 and D 2 receptors in different elements of striatal spine
modules. Drugs selective for the different striatal A 2A and CB 1 receptor heteromers could …

Functional and Neuroprotective Role of Striatal Adenosine A2A Receptor Heterotetramers

S Ferré, F Ciruela - Journal of Caffeine and Adenosine Research, 2019 - liebertpub.com
… This has been recently reported as the most probable quaternary structure of two striatal
adenosine A2A receptor (A2AR) heteromers, the postsynaptic A2AR-dopamine D2 …