Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants

P Bentley, G Peck, L Smeeth, J Whittaker, P Sharma - PloS one, 2010 - journals.plos.org
… than in controls, the 5G5G genotype – that itself is associated with elevated stroke risk relative
… We also estimated expected stroke risk on the basis of tPA levels, and its relationship with …

ACE genotype, risk and causal relationship to stroke: Implications for treatment

A Slowik, T Dziedzic, J Pera, D Wloch, G Kopec… - … treatment options in …, 2007 - Springer
… of small-vessel disease stroke. These stroke types differ with respect to stroke risk factor
profile and prognosis. It is possible that they are also different in genetic risk factor profile. Meta-…

Progress in clinical neurosciences: Migraine-stroke: A causal relationship, but which direction?

RZ Kern - Canadian journal of neurological sciences, 2004 - cambridge.org
… diathesis, or if it requires the presence of another stroke risk factor to produce … relationship
are needed to determine why migraine patients are subject to a higher risk of ischemic stroke

Common infections and the risk of stroke

AJ Grau, C Urbanek, F Palm - Nature Reviews Neurology, 2010 - nature.com
… In conclusion, the cumulative evidence presented above supports, but does not prove, a
causal relationship between periodontitis and stroke. The pathophysiological features of …

[HTML][HTML] Causal relations between exposome and stroke: A Mendelian randomization study

HQ Li, YW Feng, YX Yang, XY Leng… - … of stroke, 2022 - synapse.koreamed.org
… Finally, we identified several modifiable risk factors for stroke and stroke subtypes. Our study
provides an interventional treatment target. Optimal medication and drug compliance are of …

Causal relationship between human blood metabolites and risk of ischemic stroke: a Mendelian randomization study

M He, C Xu, R Yang, L Liu, D Zhou, S Yan - Frontiers in Genetics, 2024 - frontiersin.org
causal relationship with IS remains unclear. In this study, we systematically evaluate the
potential causal relationships … to assess the causal effects of blood metabolites on the risk of IS, …

Homocysteine and stroke: evidence on a causal link from mendelian randomisation

JP Casas, LE Bautista, L Smeeth, P Sharma… - The Lancet, 2005 - thelancet.com
… is consistent with a causal relation between homocysteine concentration and stroke. … and
risk of stroke follows a log-linear relation (table 2), and is free from confounding and reverse-…

Causal relations between obstructive sleep apnea and stroke: a Mendelian randomization study

P Li, Z Dong, W Chen, G Yang - Nature and Science of Sleep, 2023 - Taylor & Francis
… Our MR analysis found no evidence for causal effect between OSA and the risk of stroke
or its subtypes. In this study, we used the strict criteria of SNP selection and excluded an SNP …

Chronic kidney disease itself is a causal risk factor for stroke beyond traditional cardiovascular risk factors: a nationwide cohort study in Taiwan

YC Chen, YC Su, CC Lee, YS Huang, SJ Hwang - PloS one, 2012 - journals.plos.org
… We further examined the relationship of stroke risk between the study and control cohorts
younger … power to investigate the potential causal relationship of CKD itself on the risk of stroke. …

Potential new risk factors for ischemic stroke: what is their potential?

GJ Hankey - Stroke, 2006 - Am Heart Assoc
… are also newer risk factors for atherosclerotic ischemic stroke. However, proof of a causal
relationship remains … And if a causal relationship is proven, the incremental PAR of any of these …